天然气化工,环保,新材料,石油炼制,石油化工,精细化工

分析化学

胶质瘤;重型颅脑损伤;危险因素;血管痉挛;辅助治疗;脑损伤;大骨瓣开颅减压;颅内;凋亡;低级别

Colorectal Cancer;Prognosis;Apoptosis;P53;Immunotherapy;Epithelial-mesenchymal Transition;Colon Cancer;Proliferation;Cancer;Hepatic Stellate Cells

1. Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal-Epithelial Transition Factor (C-Met) Kinase and Anaplastic Lymphoma Kinase (ALK).
J. Jean Cui; Michelle Tran-Dube; Hong Shen; Mitchell Nambu; Pei-Pei Kung; Mason Pairish; Lei Jia; Jerry Meng; Lee Funk; Iriny Botrous; Michele McTigue; Neil Grodsky; Kevin Ryan; Ellen Padrique; Gordon Alton
Journal of Medicinal Chemistry, 2011

2. Hypoxia-elicited mesenchymal stem cell-derived exosomes facilitates cardiac repair through miR-125b-mediated prevention of cell death in myocardial infarction.
Ling-Ping Zhu; Tian Tian; Jun-Yao Wang; Jing-Ni He; Tong Chen; Miao Pan; Li Xu; Hui-Xin Zhang; Xue-Ting Qiu; Chuan-Chang Li; Kang-Kai Wang; Hong Shen; Guo-Gang Zhang; Yong-Ping Bai
THERANOSTICS, 2018

3. From bench to bed: the tumor immune microenvironment and current immunotherapeutic strategies for hepatocellular carcinoma
Yaojie Fu; Shanshan Liu; Shan Zeng; Hong Shen
Journal of Experimental & Clinical Cancer Research, 2019

4. Different Treatment Strategies and Molecular Features Between Right-Sided and Left-Sided Colon Cancers.
Hong Shen; Jiao Yang; Qing Huang; Meng-Jie Jiang; Yi-Nuo Tan; Jian-Fei Fu; Li-Zhen Zhu; Xue-Feng Fang; Ying Yuan
世界胃肠病学杂志英文版（电子版）, 2015

5. Transjugular Intrahepatic Portosystemic Shunt Versus Endoscopic Therapy in the Secondary Prophylaxis of Variceal Rebleeding in Cirrhotic Patients: Meta-Analysis Update.
Minghua Zheng; Yongping Chen; Jianling Bai; Qiqiang Zeng; Jie You; Rong Jin; Xiaosa Zhou; Hong Shen; Yi Zheng; Zhou Du
Journal of Clinical Gastroenterology, 2008

6. Proteome Analysis and Tissue Microarray for Profiling Protein Markers Associated with Lymph Node Metastasis in Colorectal Cancer
Haiping Pei; Hong Zhu; Shan Zeng; Yixiong Li; Huixiang Yang; Liangfang Shen; Jia Chen; Liang Zeng; Jianghong Fan; Xiaogang Li; Yuewen Gong; Hong Shen
JOURNAL OF PROTEOME RESEARCH, 2007

7. Sugemalimab Versus Placebo, in Combination with Platinum-Based Chemotherapy, As First-Line Treatment of Metastatic Non-Small-cell Lung Cancer (GEMSTONE-302): Interim and Final Analyses of a Double-Blind, Randomised, Phase 3 Clinical Trial
Caicun Zhou; Ziping Wang; Yuping Sun; Lejie Cao; Zhiyong Ma; Rong Wu; Yan Yu; Wenxiu Yao; Jianhua Chang; Jianhua Chen; Wu Zhuang; Jiuwei Cui; Xueqin Chen; You Lu; Hong Shen
LANCET ONCOLOGY, 2022

8. A Comprehensive Analysis of the Efficacy and Safety of COVID-19 Vaccines
Changjing Cai; Yinghui Peng; Edward Shen; Qiaoqiao Huang; Yihong Chen; Ping Liu; Cao Guo; Ziyang Feng; Le Gao; Xiangyang Zhang; Yan Gao; Yihan Liu; Ying Han; Shan Zeng; Hong Shen
MOLECULAR THERAPY, 2021

9. Pharmacologic Activation of P53 by Small-Molecule Mdm2 Antagonists
Hong Shen; Carl G. Maki
CURRENT PHARMACEUTICAL DESIGN, 2011

10. Design of Potent and Selective Inhibitors to Overcome Clinical Anaplastic Lymphoma Kinase Mutations Resistant to Crizotinib.
Qinhua Huang; Ted W. Johnson; Simon Bailey; Alexei Brooun; Kevin D. Bunker; Benjamin J. Burke; Michael R. Collins; Andrew S. Cook; J. Jean Cui; Kevin N. Dack; Judith G. Deal; Ya-Li Deng; Dac Dinh; Lars D. Engstrom; Mingying He
Journal of Medicinal Chemistry, 2014

1. 一种化合物苝衍生的荧光探针及其制备方法与应用
浙江大学
梅雅悦; 沈宏
公开日期: 2025-04-01 申请日期: 2022-10-14 公开号: CN115894334B

1. SOX2蛋白的磷酸化分析及其在胶质母细胞瘤中的作用和分子机制研究
立项时间: 2013-2015 项目经费：230000

2. BMP-4诱导肿瘤细胞上皮－间质转化促进肝细胞癌侵袭转移及其分子机制的研究
立项时间: 2014-2017 项目经费：850000

3. 转化生长因子TGF-β1抑制Smad1表达并激活肝脏星状细胞的机理研究
立项时间: 2008-2010 项目经费：300000

4. 结肠癌中普雷沃氏菌影响奥沙利铂化疗药敏的实验研究
立项时间: 2018

5. circRNA_100790靶向调控miR-199a-5p促进肝细胞癌增殖和侵袭转移的分子机制研究
立项时间: 2019-2020

6. VIPR1下调介导的肝细胞肝癌免疫调控作用及其分子机制研究
立项时间: 2018

7. c-Myc介导CAPRIN-1转录circRNA_100790靶向miR-199a-5p促进肝细胞癌增殖和侵袭转移的分子机制研究
立项时间: 2019-2022

8. VIP/VIPR1信号通路介导尿素循环缺陷及嘧啶从头合成抑制肝细胞癌增殖和侵袭转移的分子机制研究
立项时间: 2021

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