精细化工

1）有机合成及不对称催化2）药物及其关键中间体的高效合成方法

合成;隧底承载力;微波;家政学;萘并吡喃;亚甲基蓝;前景与构想;有机合成;越权行为;碳青霉烯

Asymmetric Catalysis;Asymmetric Synthesis;Asymmetric Hydrogenation;Hydrogenation;Palladium;Chiral Catalysts;Chiral Ligands;Iridium;Bimetallic Catalysis;Synthesis

Haipeng Wei, Yicong Luo, Jinbao Ren, Qianjia Yuan*,Wanbin Zhang*,Ni(II)-catalyzed asymmetric alkenylation and arylation of aryl ketones with organoborons via 1,5-metalate shift”,Nat. Commun.2024,15, 8775. DOI: 10.1038/s41467-024-53005-x.

Jing Guan, Yicong Luo, Qiyuan Wang, Jianzhong Chen*,Wanbin Zhang*,Copper-Catalyzed Asymmetric Hydrogenation of Unsymmetricalortho-Br Substituted Benzophenones,Angew. Chem. Int. Ed.2024,63, e202416313. DOI: 10.1002/anie.202416313.

Panpan Li, En Zheng, Guanlin Li, Yicong Luo, Xiaohong Huo, Shengming Ma,* andWanbin Zhang*, Stereodivergent access to non-natural α-amino acids via enantio- andZ/E-selective catalysis,Science2024,385, 972-979. DOI: 10.1126/science.ado4936.

Zhengdong Ding, Yicong Luo, Qianjia Yuan, Guangjie Wang, Zhenpeng Yu, Min Zhao, Delong Liu, and Wanbin Zhang*,Ru-Catalyzed Asymmetric Hydrogenation of α,β-Unsaturated γ-Lactams,J. Am. Chem. Soc.2024,146, accepted. DOI: 10.1021/jacs.4c09794.

Wenzhi Zhu, Chongyu Han, Guoqiang Yang, Xiaohong Huo*, andWanbin Zhang*, Pd/Cu-Cocatalyzed Enantio- and Diastereodivergent Wacker-Type Dicarbofunctionalization of Unactivated Alkenes.J. Am. Chem. Soc.2024,146, accepted. DOI: 10.1021/jacs.4c06788.



Jiacheng Zhang, Yicong Luo, En Zheng, Xiaohong Huo, Shengming Ma*, andWanbin Zhang*, Synergistic Pd/Cu-Catalyzed 1,5-Double Chiral Inductions.J. Am. Chem. Soc.2024,146, 9241–9251. DOI: 10.1021/jacs.4c00497.

Bowen Li, Zhiling Wang, Yicong Luo, Hanlin Wei, Jianzhong Chen,* Delong Liu, andWanbin Zhang*,Nickel-Catalyzed Asymmetric Hydrogenation for the Preparation of α-Substituted Propionic Acids.Nat. Commun.2024,15, 5482. DOI: doi.org/10.1038/s41467-024-49801-0.


Panpan Li, Zijiao Liu, Xiaohong Huo*, andWanbin Zhang*, Stereodivergent Construction of 1,5/1,7-Nonadjacent Tetrasubstituted  Stereocenters Enabled by Pd/Cu-Cocatalyzed Asymmetric Heck Cascade Reaction.Angew. Chem. Int. Ed.2024,63, e202407498. DOI: 10.1002/anie.202407498.


Youbin Peng, Guanlin Li, Chongyu Han, Yicong Luo, Xiaohong Huo*, andWanbin Zhang*, Stereodivergent Benzylic Substitution of Racemic Secondary Benzyl Esters Enabled by Pd/Cu Dual Catalysis.CCS Chem.2024, accepted. DOI: 10.31635/ccschem.024.202303749.


Huiwen Yang, Yanhua Hu, Yashi Zou, Zhenfeng Zhang,* andWanbin Zhang*. Cobalt-Catalyzed Efficient Asymmetric Hydrogenation of α-Primary Amino Ketones,JACS Au2023,accepted. DOI: 10.1021/jacsau.3c00524.


Yicong Luo, Yuqi Ma, Guanlin Li, Xiaohong Huo,* andWanbin Zhang*. Desymmetrization of Geminal Difluoromethylenes using a Palladium/Copper/Lithium Ternary System for the Stereodivergent Synthesis of Fluorinated Amino Acids,Angew. Chem. Int. Ed.2023,62,e202313838. DOI: 10.1002/anie.202313838.
(Hot paper)


Fei Li, Yicong Luo, Jinbao Ren, Qianjia Yuan,* Deyue Yan, andWanbin Zhang*.Iridium-Catalyzed Remote Site-Switchable Hydroarylation of Alkenes Controlled by Ligands,Angew. Chem. Int. Ed.2023,62, e202309859. DOI: 10.1002/anie.202309859.
(Hot paper)

Yunnan Xu, Yicong Luo, Jianxun Ye, Delong Liu, andWanbin Zhang*.Rh-Catalyzed Enantioselective Desymmetric Hydrogenation of α-Acetamido-1,3-indanediones Using Ether-Bridged Biphenyl Diphosphine Ligands.J. Am. Chem. Soc.2023,145, 21176-21182. DOI: 10.1021/jacs.3c07509.

Jing Guan, Jianzhong Chen, Yicong Luo, Lisen Guo, andWanbin Zhang*,Copper-Catalyzed Chemoselective Asymmetric Hydrogenation of C=O Bonds of Exocyclic α,β-Unsaturated Pentanones.Angew. Chem. Int. Ed.2023,62, e202306380. DOI: 10.1002/anie.202306380.

Cheng Sheng, Zheng Ling, Junzhe Xiao, Kai Yang, Fang Xie, Shengming Ma*, andWanbin Zhang*,Enantio- and Diastereoselective Synthesis of Chiral Tetrasubstituted α-Amino Allenoates Bearing a Vicinal All-Carbon Quaternary Stereocenter with Dual-Copper-Catalysis.Angew. Chem. Int. Ed.2023, 62, e202305680. DOI: 10.1002/anie.202305680.

Zhengxing Wu, Jingjie Meng, Huikang Liu, Yunyi Li, Xiao Zhang,andWanbin Zhang*,Multisite programmable functionalization of alkenes via controllable alkene isomerization.Nat. Chem.2023,15, 988-997. DOI: 10.1038/s41557-023-01209-x.

Liang Tang, Yicong Luo, Cheng Sheng, Fang Xie*, andWanbin Zhang*,  Cu-Catalyzed Asymmetric Kinetic Boron Conjugate Addition of γ-Substituted α,β-Unsaturated γ-Lactams.Angew. Chem. Int. Ed.2023,62, e202304640. DOI: 10.1002/anie.202304640.
(Hot paper)

Tiantian Chen, Yashi Zou, Yanhua Hu, Zhenfeng Zhang, Hao Wei, Liangming Wei, andWanbin Zhang*,  Cobalt-Catalyzed Efficient Convergent Asymmetric Hydrogenation ofE/Z-Enamides.Angew. Chem. Int. Ed.2023,62, e202303488. DOI: 10.1002/anie.202303488.
(Hot paper)

Yanhua Hu, Yashi Zou, Huiwen Yang, Haotian Ji, Yue Jin, Zhenfeng Zhang,* Yangang Liu, andWanbin Zhang*,Precise Synthesis of Chiral Z-Allylamides by Cobalt-Catalyzed Asymmetric Sequential Hydrogenations.Angew. Chem. Int. Ed.2023,62, e202217871. DOI: 10.1002/anie.202217871.

Ling Zhao, Yicong Luo, Junzhe Xiao, Xiaohong Huo, Shengming Ma,* andWanbin Zhang*, Stereodivergent Synthesis of Allenes with α,β-Adjacent Central Chiralities Empowered by Synergistic Pd/Cu Catalysis.Angew. Chem. Int. Ed.2023,62, e202218146. DOI: 10.1002/anie.202218146.
(Hot paper)



Hanlin Wei, Hao Chen, Jianzhong Chen*, Ilya. D. Gridnev,* andWanbin Zhang*, Nickel-Catalyzed Asymmetric Hydrogenation of α-Substituted Vinylphosphonates and Diarylvinylphosphine Oxides.Angew. Chem. Int. Ed.2023,62, e202214990. DOI: 10.1002/anie.202214990.



Yunnan Xu, Yicong Luo, Jianxun Ye, Yu Deng, Delong Liu, andWanbin Zhang*, Rh-Catalyzed Sequential Asymmetric Hydrogenations of 3-Amino-4-Chromones via an Unusual Dynamic Kinetic Resolution Process.J. Am. Chem. Soc.2022,144, 20078-20089. DOI: 10.1021/jacs.2c09266



Feng Gao, Jing Li, Tanveer Ahmad, Yicong Luo, Zhenfeng Zhang, Qianjia Yuan, Xiaohong Huo, Tao Song, andWanbin Zhang*,Sci. China Chem.2022,65, 1968-1977. DOI: 10.1007/s11426-022-1387-7.



Mo Wang,§Zhenfeng Zhang,§andWanbin Zhang*, Design, Synthesis and Application of Chiral Bicyclic Imidazole Catalysts.Acc. Chem. Res.2022,55, 2708-2727. DOI: 10.1021/acs.accounts.2c00455.
(Invited Account)



Xiaohong Huo, Guanlin Li, Xi Wang, andWanbin Zhang*, Bimetallic Catalysis in Stereodivergent Synthesis.Angew. Chem. Int. Ed.2022,61, e202210086. DOI: 10.1002/anie.202210086.
(Invited Review)



Biwen Li, Jianzhong Chen, Dan Liu, Ilya D. Gridnev, andWanbin Zhang*, Nickel-catalysed asymmetric hydrogenation of oximes.Nat. Chem.2022,14, 920-927. DOI: 10.1038/s41557-022-00971-8.

Youbin Peng, Chongyu Han, Yicong Luo, Guanlin Li, XiaohongHuo, andWanbin Zhang*, Nickel/Copper-Cocatalyzed Asymmetric Benzylation of Aldimine Esters for the Enantioselective Synthesis of α-Quaternary Amino Acids.Angew. Chem. Int. Ed.2022,61, e202203448. DOI: 10.1002/anie.202203448.
(Hot paper)

Muxing Zhou, Yashi Zou, Lu Zhang, Zhenfeng Zhang, andWanbin Zhang*, Chiral Bicyclic Imidazole-Catalyzed Direct Enantioselective C-Acetylation of Indolones.CCS Chem.2022, 5, 361-371. DOI: 10.31635/ccschem.022.202201782.

Cheng Sheng, Zheng Ling, Yicong Luo, andWanbin Zhang*, Cu-catalyzed asymmetric addition of alcohols to β,γ-alkynyl-α-imino esters for the construction of linear chiral N,O-ketals.Nat. Commun.2022,13, 400. DOI: 10.1038/s41467-022-28002-7.

Youbin Peng, Xiaohong Huo, Yicong Luo, Liang Wu, andWanbin Zhang*, Enantio- and Diastereodivergent Synthesis of Spirocycles through Dual-Metal-Catalyzed [3+2] Annulation of 2-Vinyloxiranes with Nucleophilic Dipoles.Angew. Chem. Int. Ed.2021,60, 24941-24949. DOI: 10.1002/anie.202111842.
(Hot paper)

Yunnan Xu, Delong Liu, Yu Deng, Yi Zhou, andWanbin Zhang*, Rh-Catalyzed Asymmetric Hydrogenation of 3-Benzoylaminocoumarins for the Synthesis of Chiral 3-Amino Dihydrocoumarins.Angew. Chem. Int. Ed.2021,60, 23602-23607. DOI: 10.1002/anie.202110286.

Jiacheng Zhang, Xiaohong Huo, Junzhe Xiao, Ling Zhao, Shengming Ma*, andWanbin Zhang*, Enantio- and Diastereodivergent Construction of 1,3-Nonadjacent Stereocenters Bearing Axial and Central Chirality through Synergistic Pd/Cu Catalysis.J. Am. Chem. Soc.2021,143, 12622-12632. DOI: 10.1021/jacs.1c05087.

Jian Zhang, Tiantian Chen, Yuanhao Wang, Fengfan Zhou, Zhenfeng Zhang*, Ilya D. Gridnev*, andWanbin Zhang*, Asymmetric Hydrogenation of γ-Branched Allylamines for the Efficient Synthesis of γ-Chirogenic Amines.Nat. Sci.2021, e10021. DOI: 10.1002/ntls.10021.
(Cover Picture Paper)

Yanhua Hu, Zhenfeng Zhang, Yangang Liu, andWanbin Zhang*, Cobalt-Catalyzed Chemo- and Enantioselective Hydrogenation of Conjugated Enynes.Angew. Chem. Int. Ed.2021,60, 16989-16993. DOI: 10.1002/anie.202106566.


Xiaohong Huo, Ling Zhao, Yicong Luo, Yue Wu, Yuwen Sun, Guanlin Li, Tatiana Gridneva, Jiacheng Zhang, Yong Ye, andWanbin Zhang*, Stereodivergent Pd/Cu Catalysis for Asymmetric Desymmetric Alkylation of Allylic Geminal Dicarboxylates.CCS Chem.2021,3, 1933-1944. DOI: 10.31635/ccschem.021.202101044.

Chong Liu, Jing Yuan, Zhenfeng Zhang*, Ilya D. Gridnev, andWanbin Zhang*, Asymmetric Hydroacylation Involving Alkene Isomerization for the Construction of C3-Chirogenic Center.Angew. Chem. Int. Ed.2021,60(16),8997-9002. DOI: 10.1002/anie.202017190(Very Important Paper)

Muxing Zhou, Tatiana Gridneva, Zhenfeng Zhang, Ende He, Yangang Liu, andWanbin Zhang*, Chiral Bicyclic Imidazole-Catalyzed Acylative Dynamic Kinetic Resolution for the Synthesis of Chiral Phthalidyl Esters.Angew. Chem. Int. Ed.2021,60(3), 1641-1645. DOI: 10.1002/anie.202012445(Highlighted bySYNFACTS2020,16, 1466; Very Important Paper)

Dan Liu, Bowen Li, Jianzhong Chen, Ilya D. Gridnev, Deyue Yan, andWanbin Zhang*, Ni-Catalyzed Asymmetric Hydrogenation ofN-Aryl Imino Esters for the Efficient Synthesis of Chiralα-Aryl Glycines.Nat. Commun.2020,11, 5935. DOI: 10.1038/s41467-020-19807-5(Highlighted bySYNFACTS2021,17, 0165)

Mo Wang, Lu Zhang, Xiaohong Huo, Zhenfeng Zhang, Qianjia Yuan, Panpan Li, Jianzhong Chen, Yashi Zou, Zhengxing Wu, andWanbin Zhang*, Catalytic Asymmetric Synthesis of the anti-COVID-19 Drug Remdesivir.Angew. Chem. Int. Ed.2020,59(47), 20814-20819. DOI: 10.1002/anie.202011527(Highlighted bySYNFACTS2020,16, 1350; Very Important Paper; Frontispiece)

Rui He, Xiaohong Huo, Ling Zhao, Feijun Wang, Liyin Jiang, Jian Liao*, andWanbin Zhang*, Stereodivergent Pd/Cu Catalysis for the Dynamic Kinetic Asymmetric Transformation of Racemic Unsymmetrical 1,3-Disubstituted Allyl Acetates.J. Am. Chem. Soc.2020,142(18), 8097-8103.DOI: 10.1021/jacs.0c02150(Highlighted by有机化学2020,40, 2161)

Guanlin Li, Xiaohong Huo, Xieyang Jiang, andWanbin Zhang*, Asymmetric Synthesis of Allylic CompoundsviaHydrofunctionalisation and Difunctionalisation of Dienes, Allenes, and Alkynes.Chem. Soc. Rev.2020,49(7), 2060-2118. DOI: 10.1039/c9cs00400a(ESI Highly Cited Paper; Inside Front Cover)

Yawen Hu, Jianzhong Chen, Bowen Li, Zhenfeng Zhang, Ilya D. Gridnev, andWanbin Zhang*, Nickel-Catalyzed Asymmetric Hydrogenation of 2-Amidoacrylates.Angew. Chem. Int. Ed.2020,59(13), 5371-5375. DOI: 10.1002/anie.201916534

Liang Wu, Guoqiang Yang, andWanbin Zhang*, Ni-Catalyzed Enantioconvergent Coupling of Epoxides with Alkenylboronic Acids: Construction of Oxindoles Bearing Quaternary Carbons.CCS Chem.2020,2(2), 623-631. DOI: 10.31635/ccschem.019.201900064

Yanhua Hu, Zhenfeng Zhang, Jian Zhang, Yangang Liu, Ilya D. Gridnev, andWanbin Zhang*, Cobalt-Catalyzed Asymmetric Hydrogenation of C=N Bonds Enabled by Assisted Coordination and Nonbonding Interactions.Angew. Chem. Int. Ed.2019,58(44), 15767-15771. DOI: 10.1002/anie.201909928(Highlighted bySYNFACTS2019,15, 1381 and selected as Synfact of the month)

Jian Zhang, Jia Jia, Xincheng Zeng, Yuanhao Wang, Zhenfeng Zhang, Ilya D. Gridnev, andWanbin Zhang*, Chemo- and Enantioselective Hydrogenation ofα-Formyl Enamides: An Efficient Access to Chiralα-Amido Aldehydes.Angew. Chem. Int. Ed.2019,58(33), 11505-11512. DOI: 10.1002/anie.201905263(Highlighted byAdvances In ENGINEERING; Very Important Paper)

Bowen Li, Jianzhong Chen, Zhenfeng Zhang, Ilya D. Gridnev, andWanbin Zhang*, Nickel-Catalyzed Asymmetric Hydrogenation ofN-Sulfonyl Imines.Angew. Chem. Int. Ed.2019,58(22), 7329-7334. DOI: 10.1002/anie.201902576(Very Important Paper; Inside Back Cover)

Jianzhong Chen, Zhenfeng Zhang, Bowen Li, Feilong Li, Yulin Wang, Min Zhao, Ilya D. Gridnev, Tsuneo Imamoto, andWanbin Zhang*, Pd(OAc)2-Catalyzed Asymmetric Hydrogenation of Sterically HinderedN-Tosylimines.Nat. Commun.2018,9, 5000. DOI: 10.1038/s41467-018-07462-w

Xuezhen Kou, Qihang Shao, Chenghao Ye, Guoqiang Yang*, andWanbin Zhang*, Asymmetric Aza-Wacker-Type Cyclization ofN-Ts Hydrazine-Tethered Tetrasubstituted Olefins: Synthesis of Pyrazolines Bearing One Quaternary or Two Vicinal Stereocenters.J. Am. Chem. Soc.2018,140(24), 7587-7597. DOI: 10.1021/jacs.8b02865(Highlighted bySYNFACTS2018,14, 0840)

Mao Quan, Xiaoxiao Wang, Liang Wu, Ilya D. Gridnev, Guoqiang Yang*, andWanbin Zhang*, Ni(II)-Catalyzed Asymmetric Alkenylations of Ketimines.Nat. Commun.2018,9, 2258. DOI: 10.1038/s41467-018-04645-3

Guoqiang Yang andWanbin Zhang*, Renaissance of Pyridine-Oxazolines as Chiral Ligands for Asymmetric Catalysis.Chem. Soc. Rev.2018,47(5), 1783-1810. DOI: 10.1039/c7cs00615b(Back Cover)

Xiaohong Huo, Jiacheng Zhang, Jingke Fu, Rui He, andWanbin Zhang*, Ir/Cu Dual Catalysis: Enantio- and Diastereodivergent Access toα,α-Disubstitutedα-Amino Acids Bearing Vicinal Stereocenters.J. Am. Chem. Soc.2018,140(6), 2080-2084. DOI: 10.1021/jacs.8b00187(Highlighted byOrganic Chemistry Portal; ESI Highly Cited Paper)

Xiaohong Huo, Rui He, Jingke Fu, Jiacheng Zhang, Guoqiang Yang, andWanbin Zhang*, Stereoselective and Site-Specific Allylic Alkylation of Amino Acids and Small Peptides via a Pd/Cu Dual Catalysis.J. Am. Chem. Soc.2017,139(29), 9819-9822. DOI: 10.1021/jacs.7b05460
(Highlighted bySYNFACTS2017,13, 1049 and有机化学2017,37, 2454)

Zhenfeng Zhang, Nicholas A. Butt, andWanbin Zhang*, Asymmetric Hydrogenation of Nonaromatic Cyclic Substrates.Chem. Rev.2016,116(23), 14769-14827. DOI: 10.1021/acs.chemrev.6b00564(ESI Highly Cited Paper)

Xiaohong Huo, Rui He, Xiao Zhang, andWanbin Zhang*, An Ir/Zn Dual Catalysis for Enantio- and Diastereodivergentα-Allylation ofα-Hydroxyketones.J. Am. Chem. Soc.2016,138(35), 11093-11096. DOI: 10.1021/jacs.6b06156(Highlighted bySYNFACTS2016,12, 1153 and selected as Front Cover and Synfact of the month; Highlighted byOrg. Process. Res. Dev.2016,20, 1691)

Jianzhong Chen, Zhenfeng Zhang, Delong Liu, andWanbin Zhang*, Palladium-Catalyzed Chemo- and Enantioselective C−O Bond Cleavage ofα-Acyloxy Ketones by Hydrogenolysis.Angew. Chem. Int. Ed.2016,55(29), 8444-8447. DOI: 10.1002/anie.201603590
(Highlighted bySYNFACTS2016,12, 1047 and有机化学2016,36, 1970)

Nicholas A. Butt andWanbin Zhang*, Transition Metal-Catalyzed Allylic Substitution Reactions with Unactivated Allylic Substrates.Chem. Soc. Rev.2015,44(22), 7929-7967. DOI: 10.1039/c5cs00144g(ESI Highly Cited Paper; Front Cover)

Qiupeng Hu, Zhenfeng Zhang, Yangang Liu, Tsuneo Imamoto, andWanbin Zhang*, ZnCl2-Promoted Asymmetric Hydrogenation ofβ-Secondary-Amino Ketones Catalyzed by a P-Chiral Rh–Bisphosphine Complex.Angew. Chem. Int. Ed.2015,54(7), 2260-2264. DOI: 10.1002/anie.201411384
(Highlighted bySYNFACTS2015,11, 0411 and有机化学2015,35, 1187)

Xun-Xiang Guo*, Da-Wei Gu, Zhengxing Wu, andWanbin Zhang*, Copper-Catalyzed C–H Functionalization Reactions: Efficient Synthesis of Heterocycles.Chem. Rev.2015,115(3), 1622-1651. DOI: 10.1021/cr500410y
(入选2015年中国百篇最具影响国际学术论文; ESI Highly Cited Paper)

Xiaohong Huo, Guoqiang Yang, Delong Liu, Yangang Liu, Ilya D. Gridnev*, andWanbin Zhang*, Palladium-Catalyzed Allylic Alkylation of Simple Ketones with Allylic Alcohols and Its Mechanistic Study.Angew. Chem. Int. Ed.2014,53(26), 6776-6780. DOI: 10.1002/anie.201403410

Yuanyuan Liu, Ilya D. Gridnev*, andWanbin Zhang*, Mechanism of the Asymmetric Hydrogenation of Exocyclicα,β-Unsaturated Carbonyl Compounds with an Iridium/BiphPhox Catalyst: NMR and DFT Studies.Angew. Chem. Int. Ed.2014,53(7), 1901-1905. DOI: 10.1002/anie.201309677

Jianzhong Chen, Delong Liu, Nicholas Butt, Chao Li, Dongyang Fan, Yangang Liu, andWanbin Zhang*, Palladium-Catalyzed Asymmetric Hydrogenation ofα-Acyloxy-1-arylethanones.Angew. Chem. Int. Ed.2013,52(44), 11632-11636. DOI: 10.1002/anie.201306231
(Highlighted bySYNFACTS2014,10, 0064 and有机化学2013,33, 2637)

Guoqiang Yang andWanbin Zhang*, A Palladium-Catalyzed Enantioselective Addition of Arylboronic Acids to Cyclic Ketimines.Angew. Chem. Int. Ed.2013,52(29), 7540-7544. DOI: 10.1002/anie.201302861(Highlighted bySYNFACTS2013,9, 1085)

Yuanyuan Liu andWanbin Zhang*, Iridium-Catalyzed Asymmetric Hydrogenation ofα-Alkylidene Succinimides.Angew. Chem. Int. Ed.2013,52(8), 2203-2206. DOI: 10.1002/anie.201209126(Highlighted bySYNFACTS2013,9, 0506)

Guoqiang Yang, Chaoren Shen, andWanbin Zhang*, An Asymmetric Aerobic Aza-Wacker-Type Cyclization: Synthesis of Isoindolinones Bearing Tetrasubstituted Carbon Stereocenters.Angew. Chem. Int. Ed.2012,51(36), 9141-9145. DOI: 10.1002/anie.201203693(Highlighted bySYNFACTS2012,8, 1185)

Xiaohu Zhao, Delong Liu, Hui Guo, Yangang Liu, andWanbin Zhang*, C–N Bond Cleavage of Allylic Amines via Hydrogen Bond Activation with Alcohol Solvents in Pd-Catalyzed Allylic Alkylation of Carbonyl Compounds.J. Am. Chem. Soc.2011,133(48), 19354-19357. DOI: 10.1021/ja209373k(Highlighted bySYNFACTS2012,8, 0182 andOrganic Chemistry Portal)

Zhenfeng Zhang, Fang Xie, Jia Jia, andWanbin Zhang*, Chiral Bicycle Imidazole Nucleophilic Catalysts: Rational Design, Facile Synthesis, and Successful Application in Asymmetric Steglich Rearrangement.J. Am. Chem. Soc.2010,132(45), 15939-15941. DOI: 10.1021/ja109069k(Highlighted bySYNFACTS2011,7, 0098 and有机化学2011,31, 274)

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SHANGHAI JIAO TONG UNIVERSITY
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公开日期: 2025-03-13 申请日期: 2023-03-17 公开号: US20250083126A1

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张万斌; 刘晓涛; 陈建中; 许凯; 吴良
公开日期: 2024-08-13 申请日期: 2022-04-28 公开号: CN114773168B

10. 一种手性酰胺化合物的不对称钴催化氢化制备方法
上海交通大学
张万斌; 张振锋; 陈甜甜
公开日期: 2024-06-04 申请日期: 2022-12-02 公开号: CN118125933A

11. 一种糖精的合成工艺
上海交通大学; 河南开封平煤神马兴化精细化工有限公司
张万斌; 刘德龙; 寇学振; 徐永进; 王建民; 刘辉; 李伟; 魏程; 赵鑫; 张莹
公开日期: 2024-05-24 申请日期: 2024-02-04 公开号: CN118063402A

12. 氢键辅助的手性双环咪唑有机小分子催化剂及其合成方法
上海交通大学
张万斌; 张振锋; 胡成龙; 汤旭阳; 张宝池; 王沫
公开日期: 2024-05-14 申请日期: 2022-11-02 公开号: CN118027038A

13. 不对称催化加氢制备顺式(1R,2S)-二氢茉莉酮酸甲酯的方法
上海交通大学; 江苏宏邦化工科技有限公司
张万斌; 刘晓涛; 陈建中; 寇学振; 王逸果
公开日期: 2024-05-03 申请日期: 2023-12-21 公开号: CN117964485A

14. 通过动态动力学拆分获取1S,5R-水合蒎醇的方法
上海交通大学; 江苏宏邦化工科技有限公司; 上交（淮安）新材料技术创新中心有限公司
张万斌; 陈建中; 王鹏洋; 蔡新红; 胡雅雯; 刘晓涛
公开日期: 2024-04-30 申请日期: 2023-12-08 公开号: CN117947113A

15. 一种乙烯基封端的嵌段共聚物、制备方法及应用
陕西科技大学
朱军峰; 孟睿智; 张万斌; 杨静; 李金玲
公开日期: 2024-03-08 申请日期: 2023-12-06 公开号: CN117659316A

16. 一种自修复型离子导电信息存储凝胶及其制备方法和应用
陕西科技大学
朱军峰; 陈莉君; 宋洁; 牛育华; 耿敏; 张万斌; 曾庆珠; 杨静
公开日期: 2024-02-09 申请日期: 2023-11-13 公开号: CN117534793A

17. 一种超疏水型智能响应离子和电子导电柔性电子凝胶及其制备方法和应用
陕西科技大学
朱军峰; 陈莉君; 宋洁; 李龙; 耿敏; 张万斌; 曾庆珠; 杨静
公开日期: 2024-02-09 申请日期: 2023-11-13 公开号: CN117534792A

18. 含有螯合配体的双手性金属协同催化体系及其不对称合成贝达喹啉的应用
上海交通大学
张万斌; 高峰; 李静; 坦维尔 阿哈默德; 罗亦聪; 张振锋
公开日期: 2024-01-16 申请日期: 2022-07-07 公开号: CN117399070A

19. 环己烯衍生物的不对称催化氢化方法
奥锐特药业股份有限公司; 上海交通大学
张万斌; 褚定军; 袁乾家; 谢晓强
公开日期: 2024-01-09 申请日期: 2023-10-09 公开号: CN117362142A

20. 一种双金属协同促进体系及其在不对称合成(R,S)-TBAJ-876中的应用
上海交通大学
张万斌; 高峰; 李静; 坦维尔·阿哈默德; 张振锋; 袁乾家
公开日期: 2024-01-05 申请日期: 2022-06-27 公开号: CN117343047A

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