论文著作：
[1] Qian Wang, Qian Zhang, Hua He,* Zhenzhen Feng, Jian Mao, Xiang Hu, Xiaoyun Wei, Si-min Bi, Guangyong Qin, Xiaojuan Wang, Baosheng Ge, Daoyong Yu, Hao Ren and Fang Huang* Carbon Dot Blinking Fingerprint Uncovers Native Membrane Receptor Organizations via Deep Learning. Analytical Chemistry 2022, 94(9), February 21.
[2] X. Mu, J. Wang, Hua He (co-first), Qifeng Li, Bing Yang, Junhui Wang, Haile Liu, Yalong Gao, Lufei Ouyang, Si Sun, Qinjuan Ren, Xinjian Shi, Wenting Hao, Qiaoman Fei, Jiang Yang, Lulin Li, Ryan Vest, Tony Wyss-Coray, Jian Luo, and Xiao-Dong Zhang*. An oligomeric semiconducting nanozyme with ultrafast electron transfers alleviates acute brain injury. Science Advances 2021, 7(46), eabk1210
[3] Hua He,* Xiaoliang Chen, Zhenzhen Feng, Lihua Liu, Qian Wang, and Simin Bi. Nanoscopic Imaging of Nucleolar Stress Enabled by Protein-Mimicking Carbon Dots. Nano Letters 2021, 21(13), 5689–5696
[4] Naseer Ullah Khan, Muhammad Zahir, Xukun Liu, Jing Lin, Qihong Zheng, Huajie Zhang, Samiullah Malik, Hua He ,* and Liming Shen.* Ultra-sensitive detection of exosome using biofunctionalized gold nanorods on silver-island film. Nano Letters 2021, 21(13), 5532–5539.
[5] Qian wang, Hua He,* Qian Zhang, Zhenzhen Feng, Jiqiang Li, Xiaoliang Chen, Lihua Liu, Xiaojuan Wang, Baosheng Ge, Daoyong Yu, Hao Ren and Fang Huang* Deep-Learning-Assisted Single-Molecule Tracking on a Live Cell Membrane. Analytical Chemistry 2021, 93(25), 8810–8816.
[6] Hua He, Lihua Liu, Xiaoliang Chen, Qian wang, Xiaojuan Wang, Werner M. Nau, and Fang Huang. Carbon Dot Blinking Enables Accurate Molecular Counting at Nanoscale Resolution. Analytical Chemistry 2021, 93(8), 3968–3975.
[7] Qian wang, Zhenzhen Feng, Hua He,* Jiqiang Li, Xiaoliang Chen, Lihua Liu, Xiaojuan Wang, Baosheng Ge, Daoyong Yu, Hao Ren and Fang Huang*. Nonblinking Carbon Dots for Imaging and Tracking Receptors on Live Cell membrane. Chemical Communications 2021, 57(45), 5554-5557.
[8] Hua He,* Di Liu, Zhenzhen Feng, Aijun Guo, Lihua Liu, and Xiaoliang Chen. Antifade Carbon Dots on Plasmonic Substrate for Enhanced Protein Detection in Immunotherapy. ACS Sensors 2020, 5(12), 4027-4034.
[9] Hua He, Xinjian Shi, Junying Wang, Xiaojuan Wang, Qian Wang, Daoyong Yu, Baosheng Ge, Xiaodong Zhang and Fang Huang. Reactive Oxygen Species-Induced Aggregation of Nanozymes for Neuron Injury. ACS Applied Materials & Interfaces 2020, 12(1), 209-216.
[10] Lufei Ouyang, Xiaoyu Mu, Junying Wang, Qifeng Li, Yalong Gao, Haile Liu, Si Sun, Qinjuan Ren, Ruijuan Yan, Jingya Wang, Qiang Liu, Yuanming Sun, Changlong Liu, Hua He,* Wei Long and Xiaodong Zhang*. Carbon dot targeting to nitrogen signaling molecules for inhibiting neuronal death. Journal of Materials Chemistry B 2020, 8(11), 2321-2330.
[11] Xiaoyu Mu, Hua He (co-first), Junying Wang, Wei Long, Qifeng Li, Haile Liu, Yalong Gao, Lufei Ouyang, Qinjuan Ren, Si Sun, Jingya Wang, Jiang Yang, Qiang Liu, Yuanming Sun, Changlong Liu, XiaoDong Zhang, Wenping Hu. Carbogenic Nanozyme with Ultrahigh RNS Selectivity for Traumatic Brain Injury. Nano Letters 2019, 19(7), 4527-4534.
[12] Naseer Ullah Khan, Hua He*, Xiaojuan Wang, Baosheng Ge, Qian Wang, Xu Liu, Jun Lao, Yanan Wang, Jiqiang Li, Zhencai Wang, Shitan Zhou, and Fang Huang*. A Two-Color Fluorescence Enhanced Dot-Blot Assay for Revealing Co-operative Expression of Chemokine Receptors in Cells. Chemical Communications 2018, 54, 778-781.
[13] Hua He, Shan Li, Xinjian Shi, Xiaojuan Wang, Xu Liu, Qian Wang, Aijun Guo, Baosheng Ge, Naseer Ullah Khan, and Fang Huang*, Quantitative Nanoscopy of Small Blinking Graphene Nanocarriers in Drug Delivery. Bioconjugate Chemistry 2018, 29 (11), 3658–3666.
[14] Naseer Ullah Khan, Zhenzhen Feng, Hua He*, Qian Wang, Xu Liu, Shan Li, Xinjian Shi, Xiaojuan Wang, Baosheng Ge and Fang Huang*, A Facile Plasmonic Silver Needle for Fluorescence-Enhanced Detection of Tumor Markers. Analytica Chimica Acta 2018, 1040, 120-127.
[15] Hua He, Xu Liu, Shan Li, Xiaojuan Wang, Qian Wang, Jiqiang Li, Junying Wang, Hao Ren, Baosheng Ge, Shengjie Wang, Xiaodong Zhang, Fang Huang, High-Density Super-Resolution Localization Imaging with Blinking Carbon Dots. Analytical Chemistry 2017, 89 (21), 11831-11838.
[16] Jun Lao, Hua He (co-first), Xiaojuan Wang, Zhencai Wang, Yanzhuo Song, Bin Yang, Naseer Ullahkhan, Baosheng Ge*, Fang Huang*. Single-Molecule Imaging Demonstrates Ligand Regulation of Oligomeric Status of CXCR4 in Living Cells. The Journal of Physical Chemistry B 2017, 121 (7), 1466-1474.
[17] Hua He, Zhencai Wang, Tiantian Cheng, Xu Liu, Xiaojuan Wang, Junying Wang, Hao Ren, Yawei Sun, Yanzhuo Song, Jiang Yang, Yongqing Xia, Shengjie Wang, Xiaodong Zhang*, and Fang Huang*. Visible and Near-Infrared Dual-Emission Carbogenic Small Molecular Complex with High RNA Selectivity and Renal Clearance for Nucleolus and Tumor Imaging. ACS Applied Materials & Interfaces 2016, 8 (42), 28529-28537.
[18] Hua He, Xiaojuan Wang, Tiantian Cheng, Yongqing Xia, Jun Lao, Baosheng Ge, Hao Ren, Naseer Ullah Khan, Fang Huang*. An Ultra-High Fluorescence Enhancement and High Throughput Assay for Revealing Expression and Internalization of Chemokine Receptor CXCR4. Chemistry-A European Journal 2016, 22, 5863-5867.
[19] Hua He*, Xiaojuan Wang, Zhenzhen Feng, Tiantian Cheng, Xing Sun, Yawei Sun, Yongqing Xia, Shengjie Wang, Junying Wang, Xiaodong Zhang*. Rapid microwave-assisted synthesis of ultra-bright fluorescent carbon dots for live cell staining, cell-specific targeting and in vivo imaging. Journal of Materials Chemistry B 2015, 3, 4786-4789.
[20] Hua He, Xing Sun, Xiaojuan Wang, Yawei, Sun, Hai Xu*, Jian R. Lu*. Cyclic Arginyl-Glycyl-Aspartic Acid (RGD) Peptide-Induced Synthesis of Uniform and Stable One-Dimensional CdTe Nanostructures in Aqueous Solution. RSC Advances 2014, 4, 11794-11797.
[21] Hua He, Min Feng, Jing Hu, Cuixia Chen, Jiqian Wang, Xiaojuan Wang, Hai Xu*, Jian R. Lu*. Designed Short RGD Peptides for One-Pot Aqueous Synthesis of Integrin-binding CdTe and CdZnTe Quantum Dots. ACS Applied Materials & Interfaces 2012, 4, 6362-6370.
[22] Hua He, Chao Xie, Jicun Ren*. Non-Bleaching Fluorescence of Gold Nanoparticles and Its Applications in Cancer Cell Imaging. Analytical Chemistry 2008, 80(15): 5951-5957.
[23] Hua He, Jicun Ren*. A Novel Evanescent Wave Scattering Imaging Method for Single Gold Particle Tracking in Solution and on Cell Membrane. Talanta 2008, 77(1):166-171.
[24] Hua He, Huifeng Qian, Chaoqing Dong, Kanglin Wang, Jicun Ren*. Single nonblinking CdTe quantum dots synthesized in aqueous thiopropionic acid. Angewandte Chemie International Edition 2006, 45(45): 7588-7591.
[25] Hua He, Qingji Xie, Shouzhuo Yao*. An electrochemical quartz crystal impedance study on anti-human immunoglobulin G immobilization in the polymer grown during dopamine oxidation at an Au electrode. Journal of Colloid and Interface Science 2005, 289, 446-454.
何化
山东省
研究领域：
新材料,石油炼制,石油化工,精细化工,生物医药
研究方向：
[1] 单分子/单颗粒/单细胞荧光成像分析
[2] 功能纳米探针的设计、合成及生物医学应用
[3] 表面增强荧光成像用于高灵敏生物检测和体外诊断
所在单位：
中国石油大学（华东）
