生物医药

多功能纳米载体的构建与生物医学应用；
纳米尺度上的生物分析化学

Pleurotus Ostreatus;Anticancer;Shengfu Oil;Nanoparticles;Intracellular Imaging;Antitumor Activity;Amphiphilic Beta-cd;Wound Healing;Selenium-enriched Polysaccharide;Molecularly Imprinted Polymer

1. Fret Nanoflares for Intracellular Mrna Detection: Avoiding False Positive Signals and Minimizing Effects of System Fluctuations
Yanjing Yang; Jin Huang; Xiaohai Yang; Ke Quan; He Wang; Le Ying; Nuli Xie; Min Ou; Kemin Wang
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015

2. Gold Nanoparticle Loaded Split-DNAzyme Probe for Amplified Mirna Detection in Living Cells.
Yanan Wu; Jin Huang; Xiaohai Yang; Yanjing Yang; Ke Quan; Nuli Xie; Jing Li; Changbei Ma; Kemin Wang
Analytical Chemistry, 2017

3. Gold Nanoparticle Based Hairpin-Locked-Dnazyme Probe for Amplified Mirna Imaging in Living Cells
Yanjing Yang; Jin Huang; Xiaohai Yang; Xiaoxiao He; Ke Quan; Nuli Xie; Min Ou; Kemin Wang
ANALYTICAL CHEMISTRY, 2017

4. Α-Pinene, Linalool, and 1-Octanol Contribute to the Topical Anti-Inflammatory and Analgesic Activities of Frankincense by Inhibiting COX-2.
Xiao-Jun Li; Yan-Jing Yang; Yu-Sang Li; Wei Kevin Zhang; He-Bin Tang
JOURNAL OF ETHNOPHARMACOLOGY, 2016

5. Amplified FRET Nanoflares: an Endogenous Mrna‐powered Nanomachine for Intracellular MicroRNA Imaging
Jing Li; Jiaoli Wang; Shiyuan Liu; Nuli Xie; Ke Quan; Yanjing Yang; Xiaohai Yang; Jin Huang; Kemin Wang
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020

6. Ratiometric Fluorescent Sensing of Ph Values in Living Cells by Dual-Fluorophore-Labeled I-Motif Nanoprobes
Jin Huang; Le Ying; Xiaohai Yang; Yanjing Yang; Ke Quan; He Wang; Null Xie; Min Ou; Qifeng Zhou; Kemin Wang
Analytical Chemistry, 2015

7. Aptazyme-Gold Nanoparticle Sensor for Amplified Molecular Probing in Living Cells.
Yanjing Yang; Jin Huang; Xiaohai Yang; Ke Quan; He Wang; Le Ying; Nuli Xie; Min Ou; Kemin Wang
Analytical Chemistry, 2016

8. A DNA Tetrahedron-Based Molecular Beacon for Tumor-Related Mrna Detection in Living Cells.
Nuli Xie; Jin Huang; Xiaohai Yang; Yanjing Yang; Ke Quan; He Wang; Le Ying; Min Ou; Kemin Wang
CHEMICAL COMMUNICATIONS, 2016

9. Fluorescence Resonance Energy Transfer-Based Hybridization Chain Reaction for in Situ Visualization of Tumor-Related Mrna
Jin Huang; He Wang; Xiaohai Yang; Ke Quan; Yanjing Yang; Le Ying; Nuli Xie; Min Ou; Kemin Wang
CHEMICAL SCIENCE, 2016

10. MnO2 Nanosheet Mediated “DD–A” FRET Binary Probes for Sensitive Detection of Intracellular Mrna
Min Ou; Jin Huang; Xiaohai Yang; Ke Quan; Yanjing Yang; Nuli Xie; Kemin Wang
CHEMICAL SCIENCE, 2017

1. 基于核酸放大技术的荧光探针及其构建方法和在细胞上原位可视化glycoRNA的应用
中南大学
杨艳婧; 袁盼盼; 钟世安; 龚赞; 甘雨晴; 唐亚兰
公开日期: 2025-01-14 申请日期: 2024-09-29 公开号: CN119307591A

2. 一种基于变构探针与RCA扩增技术的荧光生物传感器及其在检测金黄色葡萄球菌中的应用
中南大学
杨艳婧; 甘雨晴; 龙稀; 龚赞
公开日期: 2024-11-08 申请日期: 2024-09-24 公开号: CN118910304A

3. 一种光控荧光探针及其制备方法和应用
中南大学
杨艳婧; 李佳成; 钟世安; 罗通; 贺窅; 黄琳琳; 张婕; 刘慧; 邓志伟
公开日期: 2022-04-12 申请日期: 2021-12-24 公开号: CN114315939A

国家自然科学基金面上项目，遗传编码的荧光RNA适配体探针用于脑活性分子成像研究，54万，主持；
国家自然科学青年基金，基于多功能DNA纳米探针的癌症治疗与疗效原位评估研究，24万，主持；
湖南省自然科学基金，基于碳量子点和DNA的比率型探针在细胞表面的应用研究，5万，主持

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