新材料,石油炼制,石油化工,精细化工,生物医药

药物化学

冠状动脉疾病;预后;灌溉;食管肿瘤;食管癌;激光跟踪仪;人口老龄化;无土栽培;介入治疗;生活质量

Pyrococcus Furiosus;Lamp-1;C225;Target Therapy;Beta-catenin;DKK1;HCC;Predictor;Tumor Tissue Microarray;P-glycoprotein

1. Serum DKK1 As a Protein Biomarker for the Diagnosis of Hepatocellular Carcinoma: a Large-Scale, Multicentre Study.
Qiujin Shen; Jia Fan; Xin-Rong Yang; Yexiong Tan; Weifeng Zhao; Yang Xu; Ning Wang; Yongdong Niu; Zheng Wu; Jian Zhou; Shuang-Jian Qiu; Ying-Hong Shi; Bin Yu; Ning Tang; Wei Chu
The Lancet Oncology, 2012

2. Diagnostic and Prognostic Implications of Micrornas in Human Hepatocellular Carcinoma.
Wenxi Li; Lu Xie; Xianghuo He; Jinjun Li; Kang Tu; Lin Wei; Jun Wu; Yong Guo; Xi Ma; Pingping Zhang; Zhimei Pan; Xin Hu; Yingjun Zhao; Haiyang Xie; Guoping Jiang
International Journal of Cancer, 2008

3. Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children
Chenhong Zhang; Aihua Yin; Hongde Li; Ruirui Wang; Guojun Wu; Jian Shen; Menghui Zhang; Linghua Wang; Yaping Hou; Haimei Ouyang; Yan Zhang; Yinan Zheng; Jicheng Wang; Xiaofei Lv; Yulan Wang
EBioMedicine, 2015

4. Development of T Cells Redirected to Glypican-3 for the Treatment of Hepatocellular Carcinoma.
Huiping Gao; Kesang Li; Hong Tu; Xiaorong Pan; Hua Jiang; Bizhi Shi; Juan Kong; Hongyang Wang; Shengli Yang; Jianren Gu; Zonghai Li
CLINICAL CANCER RESEARCH, 2014

5. Plasma Phospholipid Metabolic Profiling and Biomarkers of Type 2 Diabetes Mellitus Based on High-Performance Liquid Chromatography/Electrospray Mass Spectrometry and Multivariate Statistical Analysis
C Wang; HW Kong; YF Guan; J Yang; JR Gu; SL Yang; GW Xu
Analytical Chemistry, 2005

6. A Metabonomic Study of Hepatitis B-induced Liver Cirrhosis and Hepatocellular Carcinoma by Using RP-LC and HILIC Coupled with Mass Spectrometry
Peiyuan Yin; Dafang Wan; Chunxia Zhao; Jing Chen; Xinjie Zhao; Wenzhao Wang; Xin Lu; Shengli Yang; Jianren Gu; Guowang Xu
MOLECULAR BIOSYSTEMS, 2009

7. A System-Level Investigation into the Mechanisms of Chinese Traditional Medicine: Compound Danshen Formula for Cardiovascular Disease Treatment
Xiuxiu Li; Xue Xu; Jinan Wang; Hua Yu; Xia Wang; Hongjun Yang; Haiyu Xu; Shihuan Tang; Yan Li; Ling Yang; Luqi Huang; Yonghua Wang; Shengli Yang
PLOS ONE, 2012

8. High Performance Liquid Chromatography-Mass Spectrometry for Metabonomics: Potential Biomarkers for Acute Deterioration of Liver Function in Chronic Hepatitis B.
J Yang; XJ Zhao; XL Liu; C Wang; P Gao; JS Wang; LJ Li; JR Gu; SL Yang; GW Xu
JOURNAL OF PROTEOME RESEARCH, 2006

9. Elevated Expression of DKK1 is Associated with Cytoplasmic/nuclear Beta-Catenin Accumulation and Poor Prognosis in Hepatocellular Carcinomas
Bin Yu; Xinrong Yang; Yang Xu; Genfu Yao; Huiqun Shu; Biaoyang Lin; Leroy Hoods; Hongyang Wang; Shengli Yang; Jianren Gu; Jia Fan; Wenxin Qin
JOURNAL OF HEPATOLOGY, 2009

10. The Growth and Metastasis of Human Hepatocellular Carcinoma Xenografts Are Inhibited by Small Interfering RNA Targeting to the Subunit ATP6L of Proton Pump
YD Lu; WX Qin; JJ Li; N Tan; DN Pan; HT Zhang; L Xie; GF Yao; HQ Shu; N Yao; DF Wan; JR Gu; SL Yang
CANCER RESEARCH, 2005

1. 重离子微孔膜专用生产终端控制系统
中国科学院近代物理研究所
李运杰; 莫丹; 胡正国; 夏佳文; 徐瑚珊; 段敬来; 姚会军; 刘杰; 王玥; 杨胜利; 杨雅清; 殷学军; 蒙俊; 杜衡; 谢文君
公开日期: 2023-02-03 申请日期: 2021-09-18 公开号: CN113741375B

2. 直线加速器重离子微孔膜辐照装置
中国科学院近代物理研究所
夏佳文; 莫丹; 杨雅清; 殷学军; 杨胜利; 胡正国; 李运杰; 武军霞; 曹云; 姚庆高; 高大庆; 许哲; 李忠汕
公开日期: 2021-12-17 申请日期: 2021-09-18 公开号: CN113808775A

3. 一种重离子微孔膜辐照生产装置
中国科学院近代物理研究所
李运杰; 莫丹; 胡正国; 夏佳文; 徐瑚珊; 段敬来; 姚会军; 刘杰; 王玥; 杨胜利; 杨雅清; 殷学军; 蒙俊; 杜衡; 谢文君
公开日期: 2021-12-10 申请日期: 2021-09-18 公开号: CN113769584A

4. Chimeric antigen receptors targeting GPC3 and uses thereof
Carsgen Therapeutics Limited
Zonghai Li; Huiping Gao; Hua Jiang; Bizhi Shi; Huamao Wang; Kesang Li; Hongyang Wang; Shengli Yang; Jianren Gu
公开日期: 2020-08-04 申请日期: 2014-05-06 公开号: US10731127B2

5. 编码GPC‑3嵌合抗原受体蛋白的核酸及表达GPC‑3嵌合抗原受体蛋白的T淋巴细胞
科济生物医药（上海）有限公司
李宗海; 高慧萍; 蒋华; 石必枝; 王华茂; 李克桑; 王红阳; 杨胜利; 顾健人
公开日期: 2017-12-12 申请日期: 2013-05-08 公开号: CN107460201A

6. 编码GPC‑3嵌合抗原受体蛋白的核酸及表达GPC‑3嵌合抗原受体蛋白的T淋巴细胞
上海益杰生物技术有限公司
李宗海; 高慧萍; 蒋华; 石必枝; 王华茂; 李克桑; 王红阳; 杨胜利; 顾健人
公开日期: 2017-09-29 申请日期: 2013-05-08 公开号: CN104140974B

7. Nucleic Acid Of Coded GPC3 Chimeric Antigen Receptor Protein And T Lymphocyte Expressing GPC3 Chimeric Antigen Receptor Protein
CARSGEN THERAPEUTICS LTD
LI ZONGHAI; GAO HUIPING; JIANG HUA; SHI BIZHI; WANG HUAMAO; LI KESANG; WANG HONGYANG; YANG SHENGLI; GU JIANREN
公开日期: 2016-07-28 申请日期: 2014-05-06 公开号: US2016215261A1

8. NUCLEIC ACID OF CODED GPC3 CHIMERIC ANTIGEN RECEPTOR PROTEIN AND T LYMPHOCYTE EXPRESSING GPC3 CHIMERIC ANTIGEN RECEPTOR PROTEIN
CARSGEN THERAPEUTICS LTD
LI ZONGHAI; GAO HUIPING; JIANG HUA; SHI BIZHI; WANG HUAMAO; LI KESANG; WANG HONGYANG; YANG SHENGLI; GU JIANREN
公开日期: 2016-01-08 申请日期: 2014-05-06 公开号: KR20160003287A

9. 针对磷脂酰肌醇蛋白多糖-3和T细胞抗原的双特异性抗体
SHANGHAI CANCER INST
LI ZONGHAI; WANG HUAMAO; JIANG HUA; SHI BIZHI; WANG HONGYANG; YANG SHENGLI; GU JIANREN
公开日期: 2015-11-19 申请日期: 2014-05-14 公开号: WO2015172341A1

10. 针对磷脂酰肌醇蛋白多糖-3和T细胞抗原的双特异性抗体
SHANGHAI CANCER INST
YANG SHENGLI; LI ZONGHAI; WANG HUAMAO; JIANG HUA; SHI BIZHI; WANG HONGYANG; GU JIANREN
公开日期: 2015-11-19 申请日期: 2014-05-14 公开号: WO2015172341A1

11. 表皮生长因子受体的外显子缺失变异体
上海市肿瘤研究所
李宗海; 周敏; 王海; 石必枝; 杨胜利; 王红阳; 顾健人
公开日期: 2015-04-29 申请日期: 2010-10-15 公开号: CN102443056B

12. 编码gpc3嵌合抗原受体蛋白的核酸及表达gpc3嵌合抗原受体蛋白的t淋巴细胞
SHANGHAI YIJIE BIOTECHNOLOGY CO LTD
LI ZONGHAI; GAO HUIPING; JIANG HUA; SHI BIZHI; WANG HUAMAO; LI KESANG; WANG HONGYANG; YANG SHENGLI; GU JIANREN
公开日期: 2014-11-13 申请日期: 2014-05-06 公开号: WO2014180306A1

13. 编码GPC-3嵌合抗原受体蛋白的核酸及表达GPC-3嵌合抗原受体蛋白的T淋巴细胞
上海益杰生物技术有限公司
李宗海; 高慧萍; 蒋华; 石必枝; 王华茂; 李克桑; 王红阳; 杨胜利; 顾健人
公开日期: 2014-11-12 申请日期: 2013-05-08 公开号: CN104140974A

14. Human epidermal growth factor receptor variant lacking an exon
Zonghai Li; Jianren Gu; Min Zhou; Hai Wang; Bizhi Shi; Shengli Yang; Hongyang Wang
Zonghai Li; Min Zhou; Hai Wang; Bizhi Shi; Shengli Yang; Hongyang Wang; Jianren Gu
公开日期: 2014-08-05 申请日期: 2011-10-24 公开号: US08796421B2

15. Human epidermal growth factor receptor variant lacking an exon
LI ZONGHAI; ZHOU MIN; WANG HAI; SHI BIZHI; YANG SHENGLI; WANG HONGYANG; GU JIANREN; SHANGHAI CANCER INST
LI ZONGHAI; ZHOU MIN; WANG HAI; SHI BIZHI; YANG SHENGLI; WANG HONGYANG; GU JIANREN
公开日期: 2014-08-05 申请日期: 2011-10-24 公开号: US8796421B2

16. 针对磷脂酰肌醇蛋白多糖-3和T细胞抗原的双特异性抗体
上海市肿瘤研究所
蒋华; 杨胜利; 王华茂; 王红阳; 李宗海; 石必枝; 顾健人
公开日期: 2014-06-04 申请日期: 2012-11-23 公开号: CN103833852A

17. Epidermal growth factor receptor variants and pharmaceutical compositions thereof
Zonghai Li; Hai Wang; Min Zhou; Xiaorong Pan; Jianren Gu; Shengli Yang
Zonghai Li; Hai Wang; Min Zhou; Xiaorong Pan; Jianren Gu; Shengli Yang
公开日期: 2014-04-22 申请日期: 2011-01-26 公开号: US08703917B2

18. Epidermal growth factor receptor variants and pharmaceutical compositions thereof
LI ZONGHAI; WANG HAI; ZHOU MIN; PAN XIAORONG; GU JIANREN; YANG SHENGLI; SHANGHAI CANCER INST
LI ZONGHAI; WANG HAI; ZHOU MIN; PAN XIAORONG; GU JIANREN; YANG SHENGLI
公开日期: 2014-04-22 申请日期: 2011-01-26 公开号: US8703917B2

19. Use of DKK-1 protein in the cancer diagnosis
QIN WENXIN; ZHANG HAITAO; YU YANJUN; YOU HAIYAN; YANG SHENGLI; GU JIANREN; HUANG GANG; SHENG SHILE; CHEN TAO; SHANGHAI CANCER INST
QIN WENXIN; ZHANG HAITAO; YU YANJUN; YOU HAIYAN; YANG SHENGLI; GU JIANREN; HUANG GANG; SHENG SHILE; CHEN TAO
公开日期: 2014-01-07 申请日期: 2012-08-09 公开号: US8623328B2

20. Use of DKK-1 protein in the cancer diagnosis
Wenxin Qin; Haitao Zhang; Yanjun Yu; Haiyan You; Shengli Yang; Jianren Gu; Gang Huang; Shile Sheng; Tao Chen
Wenxin Qin; Haitao Zhang; Yanjun Yu; Haiyan You; Shengli Yang; Jianren Gu; Gang Huang; Shile Sheng; Tao Chen
公开日期: 2014-01-07 申请日期: 2012-08-09 公开号: US08623328B2

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