精细化工

有机合成方法学：基于不饱和键的不对称催化；功能分子设计与合成

Heterocycles;Cyclization;Alkynes;Homogeneous Catalysis;Palladium;Asymmetric Catalysis;C-h Activation;Gold-catalyzed Reactions;Asymmetric Synthesis;Enantioselective Synthesis

1. Bo Zhou, Xiaotian Qi,* Peng Liu,* Guangbin Dong,* Development and Mechanistic Studies of the Iridium-catalyzed C−H Alkenylation of Enamides with Vinyl Acetates: A Versatile Approach for Ketone Functionalization. Angew. Chem. Int. Ed. 2021, 60, 20926.
2. Bo Zhou, Ying-Qi Zhang, Kairui Zhang, Ming-Yang Yang, Yang-Bo Chen, You Li, Qian Peng,* Shou-Fei Zhu,* Qi-Lin Zhou, Long-Wu Ye,* Stereoselective Synthesis of Medium Lactams Enabled by Metal-Free Hydroalkoxylation/Stereospecific [1,3]-Rearrangement. Nat. Commun. 2019, 10, 3234.
3. Bo Zhou, Long Li, Xin-Qi Zhu, Juan-Zhu Yan, Yi-Lin Guo, Long-Wu Ye,* Yttrium-Catalyzed Intramolecular Hydroalkoxylation/Claisen Rearrangement Sequence: Efficient Synthesis of Medium-Sized Lactams. Angew. Chem. Int. Ed. 2017, 56, 4015.
4. Peng-Fei Chen,† Bo Zhou,† Peng Wu, Binju Wang, Long-Wu Ye,* Brønsted Acid Catalyzed Dearomatization by Intramolecular Hydroalkoxylation/Claisen Rearrangement: Diastereo- and Enantioselective Synthesis of Spirolactams. Angew. Chem. Int. Ed. 2021, 60, 27164.
5. Long Li,† Bo Zhou,† Yong-Heng Wang, Chao Shu, Yi-Fei Pan, Xin Lu,* Long-Wu Ye,* Zinc-Catalyzed Alkyne Oxidation/C−H Functionalization: Highly Site-Selective Synthesis of Versatile Isoquinolones and β-Carbolines. Angew. Chem. Int. Ed. 2015, 54, 8245.
6. Bo Zhou, Tong-De Tan, Xin-Qi Zhu, Mingzhou Shang, Long-Wu Ye,* Reversal of Regioselectivity in Ynamide Chemistry. ACS Catal. 2019, 9, 6393.
7. Bo Zhou, Ying-Qi Zhang, Xin Liu, Long-Wu Ye,* Gold-Catalyzed Intermolecular Reaction of Ynamides with 3-Indolyl Azides via an Unexpected 1,2-Alkyl Migration. Sci. Bull. 2017, 62, 1201.
8. Wen-Bo Shen,† Bo Zhou,† Zhi-Xin Zhang, Han Yuan, Wei Fang, Long-Wu Ye,* Gold-Catalyzed Cascade Cyclization of N-Propargyl Ynamides: Rapid Access to Functionalized Indeno[1,2-c]pyrroles. Org. Chem. Front. 2018, 5, 2468.
9. Bo Zhou, Long Li, Xin Liu, Tong-De Tan, Jinxian Liu, Long-Wu Ye,* Yttrium-Catalyzed Tandem Intermolecular Hydroalkoxylation/Claisen Rearrangement. J. Org. Chem. 2017, 82, 10149.
10. Bo Zhou, Long Li, Long-Wu Ye,* Recent Progress in the Metal-Free or Non-Noble Metal-Catalyzed Alkyne Oxidation by Using Pyridine N-Oxide as the External Oxidant. Synlett 2016, 27, 493.

1. 铜催化基于二炔环化的轴手性化合物的不对称合成
立项时间: 2023

2. 有机催化的基于炔酰胺的轴手性分子构建新方法研究
立项时间: 2023