精细化工

1. 金属导向的有机合成方法学研究
2. 18F,13C标记的PET药物研发以及在医药领域中的创新应用
3. 精细化工产品和医药中间体的合成路线以及合成工艺的研发

2023
58. Yanan Hou, Hui Wang, Juan Xi, Ruonan Jiang, Lizhi Zhang, Xinjin Li, Fenggang Sun, Qing Liu, Zengdian Zhao and Hui Liu. Green Chem., 2023, 25, 2279-2286.
2022
57.Y. Yang, H. Wang, Z. Sun, X. Li, F. Sun, Q. Liu, L. Zhang,* L. Xu*, and H. Liu*. Palladium-Catalyzed Regiodivergent Arylamination/Aryloxygenation of Allenamide.Org. Chem. Front., 2022, 9, 5969-5975.
56.Yunxia Liu, Xin Li, Qing Liu, Xinjin Li, and Hui Liu*.Electromagnetic Mill PromotedMechanochemical Solvent-Free 2 Palladium-Catalyzed Borylation of Aryl Bromides, Org. Lett. 2022, 24, 6604−6608.
55. X. Li, Y. Liu, L. Zhang, Y. Dong, Q. Liu, D. Zhang, L. Chen, Z. Zhao and H. Liu*. A Novel Electromagnetic Mill Promoted Mechanochemical Solid-State Suzuki–Miyaura Cross-Coupling Reactions Using Ultra-Low Catalyst Loading. Green Chem., 2022, 24, 6026.
54. X. Dong, X. Sun, Y. Yang, W. Liu, B. Zheng, X. Li, D. Zhang, F. Wang and H. Liu*. Pd/Et3N·HI-Catalyzed Intramolecular C−H Alkylation to Access [a] Annulated Indoles via Highly Regioselective Ring-Opening of Epoxides. J. Org. Chem. 2022, 87, 12, 7995-8004.
53. X. Chi,. T. Xia,. Y. Yang,. T. Cao,. D. Zhang* and H. Liu*. Highly diastereoselective synthesis of an octahydro-1H-cyclpenta[c]pyridine skeleton via a Pd/Au-relay catalyzed reaction of (Z)-1-iodo-1,6-diene and alkyne. Org. Chem. Front., 2022, 9, 3186-3191.
52. L. Liang, L. Zhang*, Y. Peng*, H. Liu*. Transition-Metal Catalyzed Coupling Reactions of gem-Dibro-moviny Derivatives. Chin. J. Org. Chem. 2022, 42, 10.6023/cjoc202110026.
2021
51 X. Du, H. Zhao, X. Li, L. Zhang, Y. Dong, P. Wang, D. Zhang, Q. Liu, and H. Liu*. Ligand-Regulated Palladium-Catalyzed Regiodivergent Hydroarylation of the Distal Double Bond of Allenamides with Aryl Boronic Acid. J. Org. Chem.2021, 86, 19, 13276.
50. X. Dong, L.-P. Xu, Y. Yang, Y. Liu, X. Li, Q. Liu, L. Zheng, F. Wang and H. Liu*. A palladium/Et3N·HI-catalyzed highly selective 7-endo alkyl-Heck-type reaction of epoxides and a DFT study on the mechanism. Org. Chem. Front., 2021, 8, 6009-6018.
49. J. Li, Y. Yang, Y. Liu, Q. Liu, L. Zhang, X. Li, Y. Dong, and H. Liu. Palladium/Norbornene        Catalyzed ortho Amination/Cyclization of Aryl Iodide: Process to 3-Methyl-Indole Derivates and Controlla-ble Reductive Elimination against the Second Amination. Org. Lett., 2021, 23, 2988-2993.
48. X. Sun, X. Dong, H. Liu and Y. Liu. Recent Progress in Palladium-Catalyzed Radical Reactions. Adv. Synth. Catal. 2021, 363, 1527-1558.
47.X. Sun, D. Xu, Y. Yang, J. Fu, Y. Wang, Z. Li, Y. Liu  and  H. Liu. Palladium-Catalyzed Cascade 5-Exo-Trig Radical Cyclization/Aromatic C-H Alkylation with Unactivated Alkyl Iodides. Org. Bio. Chem., 2021, 19, 2676-2680.
46. C. Cao, Y. Yang, X. Li, Y. Liu,H. Liu,Z. Zhao, and L. Chen. Pd-Catalyzed Cascade Metallo-Ene Cyclization/Metallo-Carbene Coupling of Allenamides.Eur. J. Org. Chem.2021, 10, 1538-1542.
2020
45. J. Li, L. Meng, Q. Liu, X. Du, L.-P. Xu, L. Zhang, F.-G. Sun, X. Li, D. Zhang, X. Xiao and H.    Liu*. Palladium-Catalyzed Intramolecular Aerobic Alkenylhydroxylation of Allenamides with Alkenyl Iodides. Org. Chem. Front., 2020, 7, 3880-3886.
44. X. Dong, H. Wang, H. Liu* and F. Wang*. Recent Advanced on Transition Metal Migration         Involved Reactions. Org. Chem. Front., 2020, 7, 3530-3556.
2019年
43. M. Richard, C. Truillet, V.-L. Tran, H. Liu, K. Porte, D. Audisio, M. Roche, B. Jego, S. Cholet, F. Fenaille, B. Kuhnast, F. Taran* and S. Specklin.New fluorine-18 pretargeting PET imaging by Q2 bioorthogonal chlorosydnone–cycloalkyne click reaction. Chem. Commun., 2019, 55, 10400-10403
42. L. Meng, X. Chi, X. Sun, C. Cao, B. Ai, Q. Liu, P. Zhao, Z. Zhao, Y. Dong* and H. Liu*. An organocatalytic method for constructing pyrroles via the cycloisomerisation of Z-1-iodo-4-N-methylbenzenesulfonyl-1,6-enynes.Org. Biomol. Chem., 2019, 17, 7669-7673.
41. X. Chi, L. Meng, X. Sun, Q. Liu, B. Ai, L. Chen, D. Zhang, P. Zhao, Y. Dong, H. Liu.* Palladium-Catalyzed Cycloisomerization of (Z)-1-Iodo-1,6-dienes to 3-Aza-bicyclo[4.1.0]hept-2-enes. Asian J.Org. Chem.2019, 8, 840-843.
40. J. Song, X. Chi, L. Meng, P. Zhao, F. Sun, D. Zhang, L. Jiao, Q. Liu, Y. Dong, and H. Liu.* Pd-Catalyzed Tandem Coupling Reaction of 2-gem-Dibromovinylanilines and N-Tosylhydrazones to Construct 2-(1-phenylvinyl)-indoles. Adv. Synth. Catal. 2019, 361, 3599-3604.
39. J. Cui, L. Meng, X. Chi, Q. Liu, P. Zhao, D. Zhang, L. Chen, X. Li, Y. Dong and H. Liu.* Palladium-Catalyzed Regiocontrollable Hydroarylation Reaction of Allenamides with B2pin2/H2O. Chem. Commun., 2019, 55, 4355 – 4358.
38. F. Yan, H. Liang, B. Ai, W. Liang, L. Jiao, S. Yao, P. Zhao, Q. Liu, Y. Dong, and H. Liu.*Palladium-Catalyzed Intermolecular [4 + 2] Formal Cycloaddition with (Z)-3-Iodo Allylic Nucleophiles and Allenamides. Org. Biomol. Chem., 2019, 17, 2651 - 2656.
2018年
37. J. Cui, J. Song, Q. Liu, H. Liu,* and Y. Dong.* Transition-Metal-Catalyzed Cyanation by Using an Electrophilic Cyanating Agent, N-Cyano-N-phenyl-p-toluenesulfonamide (NCTS). Chem. Asian J. 2018, 13, 482-495. (SCI二区IF = 4.083)
36. J. Li, X. Chi, L. Meng, L. Jiao, W. Shang, P. Wang, D. Zhang, Y. Dong, Q. Liu,* and H. Liu*. Palladium-Catalyzed Heck-Type Cascade Cyclization of (Z)-1-Iodo-1,6-dienes with N-Tosyl Hydrazones. Org. Biomol. Chem., 2018, 16, 7356-7360. (SCI二区) IF = 3.56
35.H. Liang, L. Meng, X. Chi, S. Yao, H. Chen, L. Jiao, Q. Liu, D. Zhang, H. Liu,* and Y. Dong*.Palladium/Copper Co-catalyzed Cascade Metallo-ene/Sonogashira Coupling Reaction of Allenamides.Asian J. Org. Chem., 2018, 7, 1793-1796. (SCI三区IF=2.788)
34. J. Song, J. Cui, H. Liang, Q. Liu, Y. Dong, and H. Liu*. Palladium-Catalyzed Direct Oxidative Esterification of Indoles at the C3 Position: A Novel Prospect for C(sp2)-H Acyloxylation. Asian J. Org. Chem., 2018, 7, 341-345. (SCI三区IF=2.788)
33. J. Song, Q. Liu, H. Liu,* and X. Jiang.* Recent Advances in Palladium-Catalyzed Carboxylation with CO2. Eur. J. Org. Chem., 2018, 6，696-713. (SCI三区IF= 2.834)
2017年
32. X. Dong, J. Cui, J. Song, Y. Han, Q. Liu, Y. Dong and Hui Liu*. Palladium-catalyzed intramolecular reductive olefin hydrocarbonation: benzylic hydrogen serving as a new hydrogen donor. Chem. Commun., 2017, 53, 4903-4906. (Front Cover, SCI一区)
31. F. Yan, H. Liang, J. Song, J. Cui, Q. Liu, S. Liu, P. Wang, Y. Dong* and H. Liu*. Palladium-Catalyzed Cyclization-Heck Reaction of Allenamides: An Approach to 3-Methylene-5-phenyl-1,2,3,4-tetrahydropyridine Derivatives. Org. Lett., 2017, 19, 86-89. (SCI一区)
30. H. Liang,  F. Yan,   X. Dong,   Q. Liu,   X. Wei,   S. Liu,   Y. Dong*,    H. Liu*. Palladium-Catalyzed Cascade Metallo-Ene/Suzuki Coupling Reaction of Allenamides. Chem. Commun., 2017, 53, 3138-3141. (SCI一区)
29. J. Li, Y. Hu, D. Zhang, Q. Liu*, Y. Dong and H. Liu*. Transition-Metal- Catalyzed Reactions Involving Oximes. Adv. Synth. Catal., 2017, 359, 710-771. (SCI一区)
28. X. Dong, Q. Liu*, Y. Dong and H. Liu*, Transition-Metal-Catalyzed Electrophilic Amination: Application of O-Benzoylhydroxylamines in the Construction of the C-N Bond. Chem. Eur. J., 2017, 23, 2481-2511. (Frontispiece, SCI二区)
28. J. Cui, H. Wang, J. Song, X. Chi, L. Meng, Q. Liu, D. Zhang, Y. Dong and H. Liu*. Copper(I)-Catalyzed 5-exo-trig Radical Cyclization/Borylation of Alkyl Halides: Access to Functionalized Pyrrolidine Derivates. Org. Biomol. Chem., 2017, 15, 8508-8512. (SCI二区) IF = 3.56
27. X. Dong, Y. Hou, F. Meng, H-B. Liu and H. Liu*. Recent Advances on Alkyl-Heck Reaction. Chin. J. Org. Chem., 2017, 37, 1088-1098.(Invited Paper)
2016年
26. H. Liu, D. Audisio, L. Plougastel, E. Decuypere, V. Gouverneur, and F. Taran. Ultrafast Click Chemistry with Fluorosydnones. Angew. Chem. Int. Ed., 2016, 55, 12073-12077. (SCI一区)
25. J. Li, W. Yang, F. Yan, Q. Liu, P. Wang, Y. Li, Y. Zhao, Y. Dong* and H. Liu*. Pd-Catalyzed Oxidative Isomerization of Propargylic Acetates: Highly Efficient Access to α-Acetoxyenones via Alkenyl Csp2-O Bond-Forming Reductive Elimination from PdIV. Chem.Comm., 2016, 52, 10644-10647. (SCI一区)
24. X. Dong, Y. Han, F. Yan, Q. Liu*, P. Wang, K. Chen, Y. Li, Z. Zhao, Y. Dong, and H. Liu*. Palladium-Catalyzed 6 Endo Selective Alkyl-Heck Reactions: Access to 5 Phenyl-1,2,3,6-tetrahydropyridine Derivatives. Org. Lett., 2016, 18, 3774-3777. (SCI一区)
23. H. Liang, H. Liu* and X. Jiang. Synlett, 2016, 27, 2774-2782. (Invited Paper)
2015年
22. Q. Liu, X. Dong, J. Li, J. Xiao, Y. Dong* and H. Liu*. Recent Advances on Palladium Radical Involved Reactions. ACS Catal., 2015, 5, 6111-6137. (Invited Review, SCI一区)
21. E. Decuypere, S. Specklin, S. Gabillet, D. Audisio, H. Liu, L. Plougastel, S. Kolodych, F. Taran. Copper(I)-Catalyzed Cycloaddition of 4-Bromosydnones and Alkynes for the Regioselective Synthesis of 1,4,5-Trisubstituted Pyrazoles. Org. Lett., 2015, 17, 362-365. (SCI一区)
2014年以前：
20. H. Liu, J. Wei, Z. Qiao, Y. Fu, X. Jiang*. Palladium-Catalyzed Intramolecular Reductive Cross-Coupling of Csp2-Csp3 Bond Formation. Chem. Eur. J., 2014, 20, 8308-8313. (SCI二区) IF=5.16
19. H. Liu, M. Feng, X. Jiang*. Unstrained Carbon-Carbon Bond Cleavage. Chem. Asian J., 2014, 9, 3360-3382. (SCI二区)IF=3.7
18. H. Liu, X. Jiang*. Pd-Catalyzed Reactions from Unactivated Csp3-I Bond.Pure and Applied Chemistry, 2014, 85, PAC.2014.5032. IF=4.7
17. Z. Qiao,§ H. Liu,§ X. Xiao, Y. Fu, J. Wei, Y. Li* and X. Jiang*. Efficient Access to 1, 4-Benzothiazine: Palladium-Catalyzed Double C-S Bond Formation Using Na2S2O3 as Sulfuration Reagent. Org. Lett.,2013‚ 15‚ 2594-2597. (SCI一区)
16. H. Liu, Z. Gu and X. Jiang*. Direct Trifluoromethylation of C-H Bond. Adv. Synth. Catal.,2013, 355, 617-626. (SCI一区)
15. H. Liu, Xuefeng Jiang*. Transfer of Sulfur: From Simple to Diverse. Chem.Asian J., 2013, 8, 2546-2563. (SCI二区)
14. H. Liu, X. Jiang*. Mechanistic Insight to the Reaction Pathway of Aerobic Oxidative C-C Bond Cleavage of α-Hydroxy Ketones. Synlett,2013, 24, 1311-1315.
13. L. Wang, J. Huang, S. Peng, H. Liu, X. Jiang* and J. Wang*. Palladium-Catalyzed Oxidative Cycloaddition via C–H/N–H Activation: Access to Benzazepines. Angew. Chem. Int. Ed., 2013, 52, 1768-1772. (SCI一区)
12. H. Liu, C. Dong, Z. Zhang, P. Wu and X. Jiang*. Transition-Metal-Free Aerobic Oxidative Cleavage of C-C Bonds in α-Hydroxy Ketones and Mechanistic Insight to the Reaction Pathway. Angew. Chem. Int. Ed., 2012, 51, 12570-12574. (SCI一区)
11. H. Liu, Z. Qiao and X. Jiang*. Palladium-Catalyzed Atom Transfer Radical Cyclization of Unactivated Alkyl Iodide. Org. Biomol. Chem., 2012, 10, 7274-7277.
10. X. Jiang*, H. Liu and Z. Gu. Carbon-Halogen Bond Formation by the Reductive Elimination of PdII Species. Asian J. Org. Chem., 2012, 1, 16-24.
9. K. Li, J. Hu, H. Liu and X. Tong*. Amine-catalyzed formal (3+3) annulations of 2-(acetoxymethyl)buta-2,3-dienoate with sulfur ylides: synthesis of 4H-pyrans bearing a vinyl sulfide group. Chem. Commun., 2012, 48, 2900-2902.
8. W. Li, H. Liu, X. Jiang*, J. Wang*. Enantioselective Organocatalytic Conjugate Addition of Nitroalkanes to Electrophilic 2-Iminochromenes.ACS Catal., 2012, 2, 1535-1538.
7. X. Jiang*, L. Shi, H. Liu, Akbar H. Khan and Jason S. Chen. Gas Extrusion in Natural Products Total Synthesis. Org. Biomol. Chem., 2012, 10, 8383-8392.
6. P. Wu, H. Liu, X. Tong*. Synthesis of 3-pyrroline via domino Heck-aza-Michael reaction. Tetrahedron Lett., 2012, 53, 4673-4675.
5. Q. Ren, J. Huang, L. Wang, W. Li, H. Liu, X. Jiang* and J. Wang*. Highly Efficient Assembly of 3Hydroxy Oxindole Scaffold via a Catalytic Decarboxylative [1,2]-Addition Strategy. ACS Catalysis, 2012, 2, 2622-2625.
4. H. Liu, C. Li, D. Qiu* and X. Tong*. Palladium-Catalyzed Cycloisomerizations of (Z)-1-Iodo-1,6-dienes: Iodine Atom Transfer and Mechanistic Insight to Alkyl Iodide Reductive Elimination.J. Am. Chem. Soc., 2011, 133, 6187-6193.
3. H. Liu, C. Chen, L. Wang and X. Tong*. Pd(0)-Catalyzed Iodoalkynation of Norbornene Scaffolds: The Remarkable Solvent Effect on Reaction Pathway. Org. Lett., 2011, 13, 5072-5075.
2. H. Liu, L. Wang and X. Tong*. Palladium-Catalyzed Heck-type Reaction of Oxime Ether Bearing a Pendant Vinyl Iodide Moiety. Chem.Comm., 2011,47, 12206-12208.
1. H. Liu, J. Yu, L. Wang, X. Tong*. Cyclization–oxidation of 1,6-enyne derivatived from Baylis–Hillman adducts via Pd(II)/Pd(IV)-catalyzed reactions: stereoselective synthesis of multi-substituted bicyclo[3.1.0] hexanes and insight into reaction pathways. Tetrahedron Lett., 2008, 49, 6924-6928.

1. 姜雪峰，汪舰，刘会，李文军，3,3-二取代-2-氧化吲哚类化合物的不对称合成方法。
专利授权号：ZL 2012 1 0093045.9
2．姜雪峰，刘会，乔宗君，一种2,3-二氢-[1,4]-苯并噻嗪类化合物的合成方法。
专利授权号：ZL 2013 1 0028082.6
3. 刘会，刘青，董云会，李峻，胡义甜，朱玉花，一种多取代的α-乙酰氧基-α，β-烯酮类化合物的合成方法。
专利授权号：ZL 2016 1 0310198.2
4. 刘会，韩颖，董旭，刘青，董云会，许正帅，白占猛，曹风亮，一种3-甲基-1-对甲苯磺酰基四氢吡咯类化合物的合成方法。
专利授权号：ZL 2016 1 0455519.8
5. 刘会，闫法超，董旭，董云会，刘青，王平，梁寒冰，一种3-苯基-哌啶类衍生物合成方法。
专利授权号：ZL 2016 1 0518448.1
6. 刘青，董云会，刘会，李峻，董旭，闫法超，一种5,10-二氢吲哚[3,2-b]吲哚类化合物的合成方法。
专利授权号：ZL 2015 1 0911887.4
7. 刘会，刘青，董云会，董旭，韩颖，许正帅，白占猛，曹风亮，一种5-苯基-1,2,3,6-四氢吡啶衍生物的合成方法。
专利授权号：ZL 2016 1 0310197.8

1. 钯-自由基协同接力催化精准构筑Csp3-Csp3键及其机理研究，国家自然科学基金面上基金， 22078178，2021.01-2024.12
2. 非活化Csp3-Csp3键绿色化构建方法研究，山东省自然科学基金面上基金， ZR2018MB008, 2018.03-2021.06
3. 活性药物分子导向的合成化学研究创新团队，山东省高等学校青年创新团队人才引育计划，山东省教育厅
4. 钯催化非活化烷基卤代烃构建碳碳键反应方法学研究，中国博士后面上基金一等资助，2016M590736

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