精细化工

发展新型实用的均相和异相催化剂；
发展制备新型高分子功能材料的新方法；
利用高通量合成和分析方法快速构建和优化有机和高分子功能材料。

1. Le Li, Seth B. Herzon. “Temporal Separation of Catalytic Activities Allows anti-Markovnikov Ruductive Functionalization of Terminal Alkynes.” Nature Chem. 2014, 6, 22–27. (Highlighted by Sarah Abou-Shehada, Jonathan M. J. Williams. “Separated tandem catalysis: It’s about time.” Nature Chem. 2014, 6, 12–13.）
2. Le Li, Mingshuo Zeng, Seth B. Herzon. “Broad-Spectrum Catalysts for Ambient Temperature Anti-Markovnikov Hydration of Alkynes.” Angew. Chem. Int. Ed. 2014, 53, 7892–7895. (Chosen by the Editors as a “Hot Paper”.)
3. Le Li, Seth B. Herzon. “Regioselective Reductive Hydration of Alkynes to Form Branched or Linear Alcohols.” J. Am. Chem. Soc. 2012, 134, 17376–17379. (Listed as the 4th most read JACS article in November of 2012.)
4. Mingshuo Zeng, Le Li, Seth B. Herzon. “A Highly Active and Air-stable Ruthenium Complex for the Ambient Temperature Anti-Markovnikov Reductive Hydration of Terminal Alkynes.” J. Am. Chem. Soc. 2014, 136, 7058–7067.
5. Le Li, Madhu Ganesh, and Daniel Seidel. “Catalytic Enantioselective Synthesis of α,β-Diamino Acid Derivatives.”  J. Am. Chem. Soc. 2009, 131, 11648–11649. (Highlighted in “SYNFACT”, October 2009 and “JACS Select #7”, 2009.)
6. Le Li, Eric G. Klauber, and Daniel Seidel. “Catalytic Enantioselective Aldol Additions of α- Isothiocyanato Imides to Aldehydes.” J. Am. Chem. Soc. 2008, 130, 12248–12249. (Highlighted as “SYNFACT of the month,” November 2008.)