生物医药

1. 微生物化学 2. 植物化学 3. 药品、保健品、健康食品 4. 微生物菌肥 5. 高分子材料、涂料

Cytotoxicity;Antibacterial Activity;Asteraceae;Polyacetylene;Scorzonera Austriaca;Indole Alkaloids;Phytochemicals;Antioxidant;Adjuvants;Fungal Pigments

1. Xiao-Wei Guo, Zhen-Qing Yu, Junmin Xi, Hao Ren, Xin-Yu Xiang, Jia Wu, Jianguo Fang, Quan-Xiang Wu*. Isolation and Identification of Novel Antioxidant Polyketides from an Endophytic Fungus Ophiobolus cirsii LZU-1509. Journal of Agricultural and Food Chemirty, 2023, 71, 1593-1606.
2.Junmin Xi, Li-Li Tian, Jiahui Xi, Desire Girimpuhwe, Chongfei Huang, Ruixia Ma, Xiaojun Yao, Danfeng Shi, Zhongtian Bai, Quan-Xiang Wu*, Jianguo Fang. Alterperylenol as a Novel Thioredoxin Reductase Inhibitor Induces Liver Cancer Cell Apoptosis and Ferroptosis. Journal of Agricultural and Food Chemirty, 2022, 70, 15763-15775.
3. Chun-Xiao Jiang, Bo Yu, Ya-Mei Miao, Hao Ren, Qianhe Xu, Chun Zhao, Li-Li Tian, Zhen-Qing Yu, Pan-Pan Zhou, Xiaolei Wang, Jianguo Fang, Jiwen Zhang, Jin Z. Zhang, and Quan-Xiang Wu*. Indole Alkaloids from a Soil-Derived Clonostachys rosea. Jouranl of Natural Products, 2021, 84, 2468-2474.
4. Yanan Hou, Jie Li, Jun-Chen Wu, Quan-Xiang Wu,* Jianguo Fang. Activation of Cellular Antioxidant Defense System by Naturally Occurring  Dibenzopyrone Derivatives Confers Neuroprotection against Oxidative Insults. ACS Chemical Neuroscience, 2021, 12, 2798-2809.
5. Li-Li Tian, Hao Ren, Jun-Min Xi, Jianguo Fang, Jin Z. Zhang, Quan-Xiang Wu*. Diverse anti-inflammation and anti-cancer polyketides isolated from the endophytic fungi Alternaria sp. MG1. Fitoterapia, 2021, 153, 105000.
6. Jun-Chen Wu, Yanan Hou, Qianhe Xu, Xiao-Jie Jin, Yaxiong Chen, Jianguo Fang, Burong Hu, and Quan-Xiang Wu*.  (±)-Alternamgin, a Pair of Enantiomeric Polyketides, from the Endophytic Fungi Alternaria sp. MG1. Organic Letters, 2019, 21, 1551-1554.
7. Chun-Xiao Jiang, Jie Li, Jun-Min Zhang, Xiao-Jie Jin, Bo Yu, Jian-Guo Fangand Quan-Xiang Wu*. Isolation, Identification, and Activity Evaluation of Chemical Constituents from Soil Fungus Fusarium avenaceum SF-1502 and Endophytic Fungus Fusarium proliferatum AF-04. Journal of Agricultural and Food Chemirty, 2019, 67, 1839−1846.

1. 抑制植物病源真菌的倍半萜类化合物及其制备方法. 武全香，李杰，专利号CN 109400444 A，公布日：2019.03.01.

1. 国家自然科学基金面上项目，西北干旱区真菌中聚酮类新骨架分子发现及其靶向Nrf2神经保护功能研究，2023.1–2026.12, 54万，主持;
2. 国家自然科学基金面上项目，几种镰刀菌和链格孢菌中新型天然产物发现与抑制NQO1抗肿瘤功能研究，2020.1–2023.12，66万，主持;
3. 国家自然科学基金面上项目，西北特色共生菌次生代谢物发现及其基于抑制组蛋白修饰酶的抗肿瘤活性研究，2017.1–2020.12， 65万，主持;
4. 兰州市科技重大专项，兰州高原夏菜病虫害绿色防控技术开发与产业化应用，2022.6–2024.6，60万，主持；
5. 兰州大学–三棵树股份有限公司联合实验室，校企合作，2021.09–2026.08，1000万，主持；
6. 兰州大学–甘肃农垦药物碱厂特种药物联合研究中心，技术开发，2021.10‒2022.10，20万，主持；
7. 甘肃华隆芯材料科技有限公司，技术服务，2022.5–2023.5，10万，主持。

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