精细化工

有机小分子催化，药物中间体合成

1.Synthesis of five-membered cyclic nitrones based on the Lewis acid-catalysed [3+2]-annulation reaction of donor–acceptor cyclopropanes with 1,4,2-dioxazoles. Wang, Z-H, Zhang, H-H*, Xu, P-F and Luo, Y-C*. Chem. Commun. 2018, 54, 10128-10131.
2. Lewis acid catalyzed diastereoselective [3+4]-annulation of donor-acceptor cyclopropanes with anthranils: synthesis of tetrahydro-1-benzazepine derivatives. Wang, Z.-H.; Zhang, H.-H.; Wang, D.-M.; Xu, P.-F.; Luo, Y.-C.*Chem. Commun. 2017, 53, 8521-8524.
3.Lewis Acid and (Hypo)iodite Relay Catalysis Allows a Strategy for the Synthesis of Polysubstituted Azetidines and Tetrahydroquinolines. Han, J.-Q.; Zhang, H.-H., Xu, P.-F.; Luo, Y. -C.* Org. Lett. 2016, 18, 5212-5215.
4. Sc(OTf)3-Catalysed [3+3] Annulation of Cyclopropane 1,1-Diesters with Mercaptoacetaldehyde: A Facile Strategy for the Synthesis of Tetrahydrothiopyranols. Wang, H-P, Zhang, H-H,* Hu, X-Q, Xu, P-F, Luo, Y-C. Eur. J. Org. Chem. 2015, 3486.
5.TiCl4 Promoted Formal [3+3] Cycloaddition of Cyclopropane 1, 1-Diesters with Azides: Synthesis of Highly Functionalized Triazinines and Azetidines. Zhang, H.-H.; Luo, Y.-C.*; Wang, H.-P.; Chen, W.; Xu, P.-F. Org. Lett. 2014, 16, 4896-4899.
6.Sc(OTf)3-Catalyzed [3+3] Annulation of Cyclopropane 1, 1-Diesters with beta-(Indol-2-yl)-alpha,beta-unsaturated Ketones: Synthesis of Polysubstituted Tetrahydrocarbazoles. Chen, W; Zhang, H.-H., Luo, Y.-C.* Synlett 2015, 26, 1687-1692.

主持国家自然科学青年基金项目；主持甘肃省药物碱厂横向项目2项；中央高校基本科研面上项目1项。