精细化工

不对称催化合成方法学;天然产物全合成

1. “Recent Development and Applications of Semipinacol Rearrangement Reactions.” Zhang, X.-M.; Li, B.-S.;* Wang, S.-H.;* Zhang, K.; Zhang, F.-M.; Tu, Y.-Q. Chem. Sci. 2021, 12, 9262–9274.
2. “Catalytic Enantioselective Synthesis of Chiral Spirocyclic 1,3-Diketones via Organo-Cation Catalysis.” Zhang, X.-Y.; Shao, Y.-P.; Guo, B.-K.; Zhang, K.; Zhang, F.-M.; Zhang, X.-M.;* Tu, Y.-Q.* Chem. Commun. 2021, 57, 11233–11235.
3. “Collective Total Synthesis of Aspidofractinine Alkaloids through the Development of a Bischler–Napieralski/Semipinacol Rearrangement Reaction.” Wang, S.-H.; Si, R.-Q.; Zhuang, Q.-B.; Guo, X.; Ke, T.; Zhang, X.-M.;* Zhang, F.-M.;* Tu, Y.-Q.* Angew. Chem., Int. Ed. 2020, 59, 21954–21958.
4. “Enantioselective Catalytic Aldehyde α-Alkylation/Semipinacol Rearrangement: Construction of α-Quaternary-δ-Carbonyl Cycloketones and Total Synthesis of (+)-Cerapicol.” Yang, J.; Zhang, X.-M.;* Zhang, F.-M.; Wang, S.-H.; Tu, Y.-Q.;* Li, Z.; Wang, X.-C.; Wang H. Angew. Chem., Int. Ed. 2020, 59, 8471–8475.
5. “Allylic Arylation of 1,3-Dienes via Hydroboration/Migrative Suzuki−Miyaura Cross-Coupling Reactions.” Zhang, X.-M.;* Yang, J.; Zhuang, Q.-B.; Tu, Y.-Q.; Chen, Z.; Shao, H.; Wang, S.-H.; Zhang, F.-M. ACS Catal. 2018, 8, 6094-6099.
6. “A Catalytic Allylic Cation-Induced Intermolecular Allylation-Semipinacol Rearrangement.” Xu, M.-H.; Dai, K.-L.; Tu, Y.-Q.;* Zhang, X.-M.;* Zhang, F.-M.; Wang, S.-H. Chem. Commun. 2018, 54, 7685-7688.
7. “Recent Applications of the 1,2-Carbon Atom Migration Strategy in Complex Natural Product Total Synthesis.” Zhang, X.-M.; Tu, Y.-Q.;* Zhang, F.-M.; Chen, Z.-H.; Wang, S.-H.* Chem. Soc. Rev. 2017, 46, 2272-2305.
8. “Radical Aryl Migration Reactions and Synthetic Applications.” Chen Z.-M.;# Zhang X.-M.;# Tu Y.-Q.* Chem. Soc. Rev. 2015, 44, 5220-5245. (equal contribution)
9. “Total Synthesis of (+)-Alopecuridine, (+)-Sieboldine A, and (-)-Lycojapodine A.” Zhang X.-M.; Shao H.; Tu Y.-Q.;* Zhang F.-M.; Wang S.-H.* J. Org. Chem. 2012, 77, 8174-8181.
10. “Total Synthesis of (±)-Alopecuridine and Its Biomimetic Transformation into (±)-Sieboldine A.” Zhang X.-M.; Tu Y.-Q.;* Zhang F.-M.; Shao H.; Meng X. Angew. Chem., Int. Ed. 2011, 50, 3916-3919.

1. 国家自然科学基金委青年基金“Salvinorin A的不对称全合成研究”（主持）
2. 北京分子科学国家研究中心开放课题“新型氮杂卡宾金属配合物的合成与应用研究”（主持）
3. 国家自然科学基金委员会重点基金“新型手性氮杂螺环催化剂的设计合成及在手性天然药物和天然产物不对称合成中的策略性应用”（参与）
4. 国家自然科学基金委员会面上基金“新型手性螺环吡咯烷催化剂及其在不对称合成中的应用”（参与）