精细化工

1）新型过渡金属催化方法学研究
2）自由基参与的新型成键反应研究
3）具有生物活性的分子骨架设计与合成

Natural Products;Alkaloids;Heterocycles;Directed C–h Functionalization;Rearrangement;Asymmetric Total Synthesis;[3+2] Cycloaddition;Solid-phase Synthesis;Peptide Synthesis;Pyridine Derivatives

1. Divergent Total Syntheses of (-)-daphnilongeranin B and (-)-Daphenylline
Xiaoming Chen; Hai-Jun Zhang; Xinkan Yang; Houqiang Lv; Xiaoru Shao; Cheng Tao; Huifei Wang; Bin Cheng; Yun Li; Jingjing Guo; Jing Zhang; Hongbin Zhai
Angewandte Chemie, 2017

2. Synthesis of Polysubstituted Pyridines Via a One-Pot Metal-Free Strategy.
Yun Li; Ke Xiao; Bin Cheng; Huifei Wang; Lin Hu; Hongbin Zhai
Organic Letters, 2015

3. Total Synthesis of the Diterpenoid (+)‐Harringtonolide
Hai-Jun Zhang; Lin Hu; Zhiqiang Ma; Ruining Li; Zhen Zhang; Cheng Tao; Bin Cheng; Yun Li; Huifei Wang; Hongbin Zhai
Angewandte Chemie, 2016

4. A 2-(1-methylhydrazinyl)pyridine-directed C-H Functionalization/spirocyclization Cascade: Facile Access to Spirosuccinimide Derivatives.
Hua Zhao; Xiaoru Shao; Taimin Wang; Shengxian Zhai; Shuxian Qiu; Cheng Tao; Huifei Wang; Hongbin Zhai
Chemical Communications, 2018

5. Trifunctionalization of Allenes Via Cobalt-Catalyzed MHP-Assisted C–H Bond Functionalization and Molecular Oxygen Activation
Shengxian Zhai; Shuxian Qiu; Xiaoming Chen; Cheng Tao; Yun Li; Bin Cheng; Huifei Wang; Hongbin Zhai
ACS CATALYSIS, 2018

6. Rapid Construction of [5-6-7] Tricyclic Ring Skeleton of Calyciphylline Alkaloid Daphnilongeranin B
Chen Xu; Zheng Liu; Huifei Wang; Bo Zhang; Zheng Xiang; Xiaojiang Hao; David Zhigang Wang
ORGANIC LETTERS, 2011

7. Asymmetric Total Synthesis of (−)-Aspidophylline A
Taimin Wang; Xiaoguang Duan; Hua Zhao; Shengxian Zhai; Cheng Tao; Huifei Wang; Yun Li; Bin Cheng; Hongbin Zhai
Organic Letters, 2017

8. Blue-light-promoted Carbon-Carbon Double Bond Isomerization and Its Application in the Syntheses of Quinolines.
Xinzheng Chen; Shuxian Qiu; Sasa Wang; Huifei Wang; Hongbin Zhai
ORGANIC & BIOMOLECULAR CHEMISTRY, 2017

9. 2-(1-Methylhydrazinyl)pyridine as a reductively removable directing group in a cobalt-catalyzed C(sp 2 )-H bond alkenylation/annulation cascade.
Shengxian Zhai; Shuxian Qiu; Xiaoming Chen; Jiang Wu; Hua Zhao; Cheng Tao; Yun Li; Bin Cheng; Huifei Wang; Hongbin Zhai
CHEMICAL COMMUNICATIONS, 2018

10. Efficient Synthesis of Phthalimides Via Cobalt‐Catalyzed C(sp2)−H Carbonylation of Benzoyl Hydrazides with Carbon Monoxide
Shuxian Qiu; Shengxian Zhai; Huifei Wang; Cheng Tao; Hua Zhao; Hongbin Zhai
Advanced synthesis & catalysis, 2018