生物医药

天然药物分离，多功能分离材料的设计与制备

⟡Jie-Ping Fan, Ping Xie, Chao Yuan, Shu-Hong Feng, Hui-Ping Chen, Hai-Long Peng, Chun-Fang Xie*. Construction and properties of a betulinic acid based low molecular-weight supramolecular hydrogel. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2026, 730: 139013.
⟡Yi-Jun Cao, Zi-Ying Chen, Hai-Long Peng, Hui-Ping Chen*, Chun-Fang Xie*, Jie-Ping Fan*, One-step electrochemical synthesis of Zn-MOFs/NF composite electrodes for efficient electrosorption of organic dyes. Separation and Purification Technology, 2025, 360, 131020.
⟡Jie-Ping Fan, Xiang Li, Zhi-Tao Lai, Yu-Tian Feng, Hui-Ping Chen, Li-Peng Zhong, Chun-Fang Xie*. Electro-spinning a calcium alginate based molecular imprinted nanofiber membrane for selectively adsorbing cytochrome c. Separation and Purification Technology, 2025, 356, 129877.
⟡Jie-Ping Fan, Ping Gan, Feng-Hui Tao, Hui-Ping Chen, Hai-Long Peng, Yu-De Liu, Chun-Fang Xie*. Preparation of a Molecularly Imprinted Poly(OA[AMI] Supramolecular Hydrogel) for selectively enriching Oleanolic Acid. Separation and Purification Technology, 2024, 340, 126726.
⟡Jie-Ping Fan, Jia-Ming Tian, Hui Zhong, Han-Qing Chen, Chun-Fang Xie*, Hui-Ping Chen, Hai-Long Peng, Yu-De Liu. Synthesis of a porous hollow magnetic molecularly imprinted microsphere by O/W/O composite emulsion polymerization for specifically recognizing bovine serum albumin. Separation and Purification Technology, 2024, 329, 125197.
⟡Jie-Ping Fan, Jia-Hui Lai, Cong-Bo Huang, Zhi-Tao Lai, Chun-Fang Xie*, Hui-Ping Chen, Hai-Long Peng, Yu-De Liu. Synthesis of a gelatin based molecularly imprinted hydrogel with high selectivity on adsorbing bovine serum albumin. Separation and Purification Technology, 2024, 328, 124999.
⟡Jie-Ping Fan, Zhi-Tao Lai, Dong-Yang Mao, Chun-Fang Xie*, Hui-Ping Chen, Hai-Long Peng. Preparation of a silk fibroin/gelatin composite hydrogel for high-selectively adsorbing bovine hemoglobin. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2023, 660: 130869.
⟡Jie-Ping Fan, Ban-Tian He, Yi Gao, Chun-Fang Xie*, Hui-Ping Chen, Hai-Long Peng. Biphasic alcoholysis coupled with high speed countercurrent chromatography for high performance on separating phorbol from Croton tiglium Linn extracts. Journal of Separation Science, 2023: 2200984.
⟡Jie-Ping Fan, Feng-Hui Tao, Xue-Hong Zhang, Tian-Tao Yuan, Chun-Fang Xie*, Hui-Ping Chen, Hai-Long Peng. Synthesis of an ursolic acid organic salt based low-molecular-weight supramolecular hydrogel with unique thermo-responsiveness behavior. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022, 652: 129839.
⟡Jie-Ping Fan, Chao Yuan, Xiao-Hui Lai, Chun-Fang Xie*, Hui-Ping Chen, Hai-Long Peng. Density, viscosity and electrical conductivity of four amino acid based ionic liquids derived from L-Histidine, L-Lysine, L-Serine, and Glycine. Journal of Molecular Liquids, 2022, 364: 119944.
⟡Jie-Ping Fan, Cong-Bo Huang, Yu-Tong Chen, Chun-Fang Xie*, Hui-Ping Chen, Hai-Long Peng. Silk fibroin/calcium alginate composite modifying supermacroporous molecularly imprinted membrane synthesis for high performance on recognizing bovine hemoglobin. Journal of Applied Polymer Science, 2022, 139(35): e52842.
⟡Chunfang Xie, Matyas A. Bittenbinder, Julien Slagboom, Arif Arrahman, Sven Bruijns, Govert W. Somsen, Freek J. Vonk, Nicholas R. Casewell, Juan J. García-Vallejo, Jeroen Kool. Erythrocyte haemotoxicity profiling of snake venom toxins after nanofractionation. Journal of Chromatography B, 2021, 1176: 122586.
⟡Chunfang Xie, Julien Slagboom, Laura-Oana Albulescu, Govert W. Somsen, Freek J. Vonk, Nicholas R. Casewell, Jeroen Kool. Neutralising effects of small molecule toxin inhibitors on nanofractionated coagulopathic Crotalinae snake venoms. Acta Pharmaceutica Sinica B, 2020, 10(10): 1835-1845.
⟡Chunfang Xie, Laura-Oana Albulescu, Kristina B. M. Still, Julien Slagboom, Yumei Zhao, Zhengjin Jiang, Govert W. Somsen, Freek J. Vonk, Nicholas R. Casewell, Jeroen Kool. Varespladib inhibits the phospholipase A2 and coagulopathic activities of venom components from hemotoxic snakes. Biomedicines, 2020, 8(6): 165.
⟡Chunfang Xie, Laura-Oana Albulescu, Mátyás A. Bittenbinder, Govert W. Somsen, Freek J. Vonk, Nicholas R. Casewell, Jeroen Kool. Neutralizing effects of small molecule inhibitors and metal chelators on coagulopathic Viperinae snake venom toxins. Biomedicines, 2020, 8(9): 297.
⟡Chunfang Xie, Julien Slagboom, Laura-Oana Albulescu, Ben Bruyneel, Kristina B. M. Still, Freek J. Vonk, Govert W. Somsen, Nicholas R. Casewell, Jeroen Kool. Antivenom neutralization of coagulopathic snake venom toxins assessed by bioactivity profiling using nanofractionation analytics. Toxins, 2020, 12(1): 53.
⟡Laura-Oana Albulescu, Chunfang Xie, Stuart Ainsworth, Jaffer Alsolaiss, Edouard Crittenden, Charlotte A. Dawson, Rowan Softley, Keirah E. Bartlett, Robert A. Harrison, Jeroen Kool, Nicholas R. Casewell. A therapeutic combination of two small molecule toxin inhibitors provides pancontinental preclinical efficacy against viper snakebite. Nature Communications, 2020, 11(1): 6094.