精细化工,生物医药

主要利用X-射线晶体学等结构生物学技术对酶类生物催化剂进行结构功能研究，从基因数据库中发掘出有潜在工业应用价值的酶类催化剂，对它们进行表达纯化、X射线晶体学工作，了解相关催化剂的机理以及特性。在此基础上，通过理性、半理性设计改进酶的效能，如拓展底物谱、提高酶活、耐温性能等，以增强它们的工业应用潜能。

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