生物医药

工业丝状真菌代谢工程改造，致力于丝状真菌生物质降解利用调控机制

Zhao Z, Gu S, Liu D, Liu D, Chen B,Li J*, Tian C*. The putative methyltransferase LaeA regulates mycelium growth and cellulase production inMyceliophthora thermophila. Biotechnology for Biofuels and Bioproducts. 2023;16(1).
Wu T, Li J*, Tian C*. Fungal carboxylate transporters: recent manipulations and applications. Appl Microbiol Biotechnol. 2023.
Gu S#, Zhao Z#, Xue F, Liu D, Liu Q, Li J*, Tian C*. The arabinose transporter MtLat-1 is involved in hemicellulase repression as a pentose transceptor in Myceliophthora thermophila. Biotechnol Biofuels Bioprod. 2023;16(1):51.
Wu T, Wang Y, Li J*, Tian C*. Dissecting key residues of a C4-dicarboxylic acid transporter to accelerate malate export in Myceliophthora. Appl Microbiol Biotechnol. 2022.
Gu S, Zhao Z, Yao Y, Li J*, Tian C*. Designing and Constructing a Novel Artificial Pathway for Malonic Acid Production Biologically. Front Bioeng Biotechnol. 2022;9.
Wang H, Sun T, Zhao Z, Gu S, Liu Q, Wu T, Wang D, Tian C, Li J*. Transcriptional Profiling of Myceliophthora thermophila on Galactose and Metabolic Engineering for Improved Galactose Utilization. Front Microbiol. 2021;12.
Li J#, Chen B#, Gu S#, Zhao Z, Liu Q, Sun T, Zhang Y, Wu T, Liu D, Sun W, Tian C*. Coordination of consolidated bioprocessing technology and carbon dioxide fixation to produce malic acid directly from plant biomass in Myceliophthora thermophila. Biotechnol Biofuels. 2021;14(1):186.
Li J, Lin L, Sun T, Xu J, Ji J, Liu Q, Tian C*. Direct production of commodity chemicals from lignocellulose using Myceliophthora thermophila. Metab Eng. 2019;61 (2020 ):416–26.
Liu Q#, Li J#, Gao R#, Li J, Ma G, Tian C*. CLR-4, a novel conserved transcription factor for cellulase gene expression in ascomycete fungi. Mol Microbiol. 2019;111(2):373-94.
Xu G#, Li J#, Liu Q#, Sun W, Jiang M, Tian C*. Transcriptional analysis of Myceliophthora thermophila on soluble starch and role of regulator AmyR on polysaccharide degradation. Bioresour Technol. 2018;265:558-62.