论文著作：
1. Zhang YB, Xiao G, Ding HY, Zou Q, Gu D, Wen JC, Pei YG, Guo RX*, Wang QY*, Zhou XH*. Direct sensing of host ferric iron by an archetype histidine kinase mediates virulence of an enteric pathogen. Proc Natl Acad Sci U S A 2025, 122, e2507874122.
2. Ding HY, Ahat P , Song W, Zhang YX, Zhang YB*, Wang QY*. Transposon insertion sequencing analysis reveals conditional essential genes for infection in Pseudomonas plecoglossicida. Aquaculture 2025, 607.
3. Wang L, Li YM, Wang PB, Zhang YB*, Liu Q*. Enhanced recombinase polymerase amplification via UvsX engineering and reaction optimization for rapid detection of Vibrio parahaemolyticus. Lett Appl Microbiol 2025, 78:ovaf081.
4. Zhang SJ, Zhang YX, Liu Q, Wang QY, Zhang YB*. A recombinase polymerase amplification with lateral flow assay for rapid on-the-spot detection of Aeromonas salmonicida. Water Biol Secur 2024, 3: 100272.
5. Zhang YB, Huang YP, Ding HY, Ma JB, Tong XY, Zhang YX, Tao Zhen*, Wang QY*. A σE-mediated temperature gauge orchestrates type VI secretion system, biofilm formation and cell invasion in pathogen Pseudomonas plecoglossicida. Microbiol Res 2023, 266:127220.
6. Zhang YB#, Wu X#, Cai JX, Chen M, Zhang J, Shao S, Zhang YX, Ma Y*, Wang QY*. Transposon insertion sequencing analysis unveils novel genes involved in luxR expression and quorum sensing regulation in Vibrio alginolyticus. Microbiol Res 2023, 267:127243.
7. Cai JX, Zhou MQ, Zhang YX, Ma Y*, Zhang YB*, Wang QY. Identification of determinants for entering into a viable but nonculturable state in Vibrio alginolyticus by Tn-seq. Appl Microbiol Biotechnol 2023, 107:1813-1827.
8. Wang Y, Jin YH, Sun F, Zhang YX, Liu Q, Wang QY, Yang DH, Zhang YB*. The c-di-GMP signalling component YfiR regulates multiple bacterial phenotypes and virulence in Pseudomonas plecoglossicida. J Appl Microbiol 2023, 134:lxad157.
9. Cai JX, Hao Y, Xu RJ, Zhang YX, Ma Y, Zhang YB*, Wang QY. Differential binding of LuxR in responses to temperature gauges switches virulence gene expression in Vibrio alginolyticus. Microbiol Res 2022, 263:127114.
10. Mao QQ, Jiang JH, Wu X, Ma Y, Zhang YX, Zhao YN*, Zhang YB*, Wang QY. The bifunctional alcohol/aldehyde dehydrogenase AdhE controls phospho-transferase system (PTS) sugar utilization and virulence gene expression by interacting PtsH in pathogen Edwardsiella piscicida. Microbiol Res 2022, 260:127018.
11. Hu MZ#, Zhang YB#, Gu D, Chen X, Waldor MK*, Zhou XH*. Nucleolar c-Myc recruitment by a Vibrio T3SS effector promotes host cell proliferation and bacterial virulence. EMBO J 2021, 40:e105699.
12. Gu D#, Zhang YB#, Wang QY#, Zhou XH*. S-nitrosylation-mediated activation of a histidine kinase represses the type 3 secretion system and promotes virulence of an enteric pathogen. Nat Commun 2020, 11:5777.
13. Zhang YB, Liu HH, Gu D, Lu XX, Zhou XH*, Xia XD*. Transcriptomic analysis of PhoR reveals its role in regulation of swarming motility and T3SS expression in Vibrio parahaemolyticus. Microbiol Res 2020, 235: 126448.
14. Zhang YB, Qiao HO, Chen C, Wang ZL, Xia XD*. Determination of nitrofurans metabolites residues in aquatic products by ultra-performance liquid chromatography–tandem mass spectrometry. Food Chemistry 2016, 192:612-617.
张艺蓓
上海市
研究领域：
生物医药
研究方向：
1）病原的分子致病机理研究：采用多组学技术系统鉴定典型病原菌的关键毒力因子及其在体内外定植与存活相关基因；重点研究细菌毒力分泌系统在介导病原-环境信号-宿主互作网络中的作用机制，及其对毒力与代谢的调控规律，揭示病害发生与传播的分子基础，为疫苗的理性设计与靶点筛选提供理论依据。
2）病害免疫防控技术、绿色控制策略及病原快检技术开发：依托前期基础研究成果，开展疫苗创制与合成生物技术研究，推动疫苗产品的开发与产化转化。同时开发病害绿色防控新策略和现场快速检测技术，为养殖过程中病原的全链条监测与病害高效控制提供关键技术支撑。
所在单位：
华东理工大学
