论文著作：
1. Zhuang Wang, Yuanyuan Liu, Jing Hu, Xinwei You, Jin Yang, Yuanxing Zhang, Qin Liu, Dahai Yang*. Tissue-resident trained immunity in hepatocytes protects against septic liver injury in zebrafish. Cell Reports 2024, 43: 114324.
2. Zhuang Wang, Jing Hu, Zhengkang Mei, Yuanxing Zhang, Qin Liu, Dahai Yang*. Mannan-oligosaccharide induces trained immunity activation and alleviates pathological liver injury in turbot (Scophthalmus maximus). Aquaculture 2024, 578: 740097.
3. Zhuang Wang, Xinwei You, Yuanxing Zhang, Qin Liu, Dahai Yang*. Poly(I:C) induces anti-inflammatory response against secondary LPS challenge in zebrafish larvae. Fish Shellfish Immunol 2024, 144: 109285.
4. Zhuang Wang, Zhaoyan Gu, Qing Hou, Weijie Chen, Di Mu, Yuanxing Zhang, Qin Liu, Zhihong Liu, Dahai Yang*. Zebrafish GSDMEb cleavage-gated pyroptosis drives septic-acute kidney injury in vivo. J Immunol 2020, 204: 1929-1942.
5. Zhuang Wang, Lingyun Lin, Weijie Chen, Xin Zheng, Yuanxing Zhang, Qin Liu, Dahai Yang*. Neutrophil plays critical role during Edwardsiella piscicida immersion infection in zebrafish larvae. Fish Shellfish Immunol 2019, 87: 565-572.
6. Zhenhe Xu, Zihan Ding, Lijia Shi, Yuzhen Xie, Yuanxing Zhang, Zhuang Wang**, Qin Liu*. Coevolution between marine Aeromonas and phages reveals temporal trade-off patterns of phage resistance and host population fitness. ISME J 2023, 17: 2200-2209.
7. Feizi Hu, Zhuang Wang*, Yuanxing Zhang, Dahai Yang, Qin Liu. TLR5b-mediated NF-κB activation promotes neutrophil recruitment to defense Edwardsiella piscicida infection in zebrafish. Aquaculture 2023, 564: 739041.
8. Jingjing Zhao, Weijie Chen, Yuanxing Zhang, Qin Liu, Dahai Yang, Zhuang Wang*. Bacterial infection induces pyroptotic signaling-mediated neutrophil extracellular traps (NETs) formation in turbot (Scophthalmus maximus), Fish Shellfish Immunol 2022, 127: 982-990.
9. Di Mu, Yu Jiang, Jing He, Yuanxing Zhang, Dahai Yang, Qin Liu, Zhuang Wang*. Dietary supplementation of propolis enhanced the innate immune response against Edwardsiella piscicida challenge in turbot (Scophthalmus maximus). Fish Shellfish Immunol 2022, 124: 273-279.
10. Feizi Hu, Yuanxing Zhang, Qin Liu, Zhuang Wang*. PurA facilitates Edwardsiella piscicida to escape NF-κB signaling activation. Fish Shellfish Immunol2022, 124: 254-260.
11. Hao Chen, Xiaomin Wu, Zhaoyan Gu, Shouwen Chen, Xiangshan Zhou, Yuanxing Zhang, Qin Liu, Zhuang Wang**, Dahai Yang*.Zebrafish gasdermin E cleavage-engaged pyroptosis by inflammatory and apoptotic caspases. Dev Comp Immunol 2021, 124: 104203.
王壮
上海市
研究领域：
生物医药
研究方向：
训练免疫是近年来发现的一种先天免疫记忆模式，课题组围绕鱼类先天免疫调控宿主免疫稳态这一关键科学问题，以训练免疫为切入点开展鱼类病害免疫防控相关研究工作如下：
1. 训练免疫调控鱼类感染性器官损伤分子机制研究；
2. 基于训练免疫的水产免疫生物制品开发与应用；
所在单位：
华东理工大学
