生物医药

极端微生物资源挖掘及元器件应用、发酵过程优化等

1、Huo XY, Yang HL, Feng SS*. Insights into the defensive mechanism of bioleaching microorganisms under extreme environmental copper stress. Reviews in Environmental Science and Bio/Technology, 2023, 22:79–103.
2、Qiu YK, Tong YJ, Yang HL, Feng SS*. Molecular insights into a novel Cu(I)-sensitive ArsR/SmtB family repressor in extremophile Acidithiobacillus caldus. Applied and Environmental Microbiology, 2023, 89:e0126622.
3、Jiang ZM, Lu J, Tong YJ, Yang HL, Feng SS*. Enhancement of acid tolerance of Escherichia coli by introduction of molecule chaperone CbpA from extremophile. World Journal of Microbiology and Biotechnology, 2023, 39:158.
4、Yin YJ, Tong YJ, Yang HL, Feng SS*. EpsRAc is a copper-sensing MarR-family transcriptional repressor from Acidithiobacillus caldus. Applied Microbiology and Biotechnology, 2022, 106:3679–3689.
5、Gong LQ, Tong YJ, Yang HL, Feng SS*. Simultaneously pollutant removal and S0 recovery from composite wastewater containing Cr(VI)-S2- based on biofilm enhancement. Bioresource Technology, 2022, 351:127017.
6、Hou SX, Tong YJ, Yang HL, Feng SS*. Molecular insights into the copper-sensitive operon repressor in Acidithiobacillus caldus. Applied and Environmental Microbiology, 2021, 87:e00660-21.
7、Feng SS, Qiu YK, Huang ZZ, Yin YJ, Zhang HL, Zhu DQ, Tong YJ, Yang HL*. The adaptation mechanisms of Acidithiobacillus caldus CCTCC M 2018054 to extreme acid stress: Bioleaching performance, physiology, and transcriptomics. Environmental Research, 2021, 199:111341.
8、Feng SS, Jiang ZM, Chen YQ, Gong LQ, Tong YJ, Zhang HL, Huang X, Yang HL*. Simultaneous denitrification and desulfurization-S0 recovery of wastewater in trickling filters by bioaugmentation intervention based on avoiding collapse critical points. Journal of Environmental Management, 2021, 292:112834.
9、Feng SS, Yin YJ, Yin ZW, Zhang HL, Zhu DQ*, Tong YJ, Yang HL*. Simultaneously enhance iron/sulfur metabolism in column bioleaching of chalcocite by pyrite and sulfur oxidizers based on joint utilization of waste resource. Environmental Research, 2021, 194:110702.
10、Hu WB#, Feng SS*#, Tong YJ, Zhang HL, Yang HL*. Adaptive defensive mechanism of bioleaching microorganisms under extremely environmental acid stress: Advances and perspectives. Biotechnology Advances, 2020, 42, 107580.

1、冯守帅，杨海麟，尹伊君，仝艳军，陆潇阳，邱永康. 一种喜温嗜酸硫杆菌来源EpsRAc转录调控因子及其在耐受铜氧化方面的应用，ZL202111230051.X
2、冯守帅，杨海麟，龚良琪，仝艳军，蒋振明. 一种基于生物膜强化同步脱硫反硝化处理工业废水的方法，ZL2021115366580
3、冯守帅，杨海麟，崔亚铨，尹宗伟，侯少翔. 一株嗜酸喜温硫杆菌及其应用，ZL2018114740743
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6、冯守帅，杨海麟，黄壮壮，尹宗伟，侯少翔. 一种基于铁硫代谢调控提高嗜酸硫杆菌生物浸出资源化组合方法，ZL201810980270.1
7、冯守帅，杨海麟，张燕可. 一株芳香烃的高效降解菌及其应用，ZL201610045801.9
8、冯守帅，杨海麟，詹晓，王武，辛瑜，夏小乐，张玲. 一株高效降解DBT类的脱硫菌及其在脱硫方面的应用，ZL201510005497.0

1、国家重点研发计划“前沿生物技术”重点专项子课题，基于复杂系统理论的智能生物制造与发酵优化调控技术（2022YFC3401304/001），在研。
2、国家自然科学基金面上项目（32371540），多功能因子EpsR调控Acidithiobacillus caldus生物膜定植机制，在研。
3、国家自然科学基金面上项目（21878128），高铜-强酸双重胁迫下嗜酸喜温硫杆菌铜转运系统和硫代谢协作抗逆机制，已结题。
4、国家自然科学基金面上项目（21776113），嗜酸氧化硫硫杆菌硫氧化调控生理机制解析，已结题。
5、国家自然科学基金青年项目（21606110），嗜酸硫杆菌对黄铜矿浸出中钝化胁迫的生理应答机制，已结题。
6、江苏省自然科学基金项目（BK20150133），基于关键微生物群落结构的定向调控削弱黄铜矿浸出过程中钝化效应研究，已结题。

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