生物医药

生物高分子与胶体，聚电解质，水凝胶

1. Zhan, Q.-W.; Gao, J.; Li, D.; Huang, Y.*, High throughput onion-like liposome formation with efficient protein encapsulation under flash antisolvent mixing. J. Colloid Interf. Sci. 2022, 618, 185-195.
2. Yuan, Y.; Gao, J.; Zhai, Y.; Li, D.; Huang, Y.*, Mixing efficiency affects the morphology and compactness of chitosan/tripolyphosphate nanoparticles. Carbohydr. Polym. 2022, 119331.
3. Gao, J.; Zhan, Q.-W.; Tang, Z.; Huang, Y.*, The Critical Transition from Soluble Complexes to Colloidal Aggregates of Polyelectrolyte Complexes at Non-Stoichiometric Charge Ratios. Macromolecular Rapid Communications 2022, 2100880.
4. Zhan, Q.-W.; Huang, Y.*, Continuous and large-scale fabrication of lecithin stabilized nanoparticles with predictable size and stability using flash nano-precipitation. LWT 2021, 139, 110558.
5. Lin, J.; Huang, Y.*; Wang, S.*, The Hofmeister effect on protein hydrogels with stranded and particulate microstructures. Colloids and Surfaces B 2020, 196, 111332.
6. Yuan, Y.; Huang, Y.*, Ionically Crosslinked Polyelectrolyte Nanoparticle Formation Mechanisms: The Significance of Mixing. Soft Matter 2019, 15 (48), 9871-9880.
7. He, Q.; Huang, D.; Yang, J.; Huang, Y.*; Wang, S.*, Dual Cross-Link Networks to Preserve Physical Interactions Induced by Soaking Methods: Developing a Strong and Biocompatible Protein-Based Hydrogel. ACS Appl. Bio Mater. 2019, 2 (8), 3352-3361.
8. Ding, L.; Huang, Y.*; Cai, X.; Wang, S.*, Impact of pH, ionic strength and chitosan charge density on chitosan/casein complexation and phase behavior. Carbohydr. Polym. 2019, 208, 133-141.
9. He, Q.; Huang, Y.*; Wang, S.*, Hofmeister Effect-Assisted One Step Fabrication of Ductile and Strong Gelatin Hydrogels. Adv. Func. Mater. 2018, 28, 1705069. (AFM当月热点文章Top 10)
10. Huang, Y. and Y. Lapitsky., On the kinetics of chitosan/tripolyphosphate micro- and nanogel aggregation and their effects on particle polydispersity. J. Colloid Interf. Sci. 2017, 486, 27-37.
11. Huang, Y.; Cai, Y; Lapitsky, Y., Factors affecting the stability of chitosan/tripolyphosphate micro- and nanogels: resolving the opposing findings. J. Mater. Chem. B 2015, 3, 5957-5970.
12. Huang, Y.; Lawrence, P.; Lapitsky, Y., Self-assembly of stiff, adhesive and self-healing gels from common polyelectrolytes. Langmuir 2014, 30, 7771-7777. (front cover)
13. Huang, Y.; Lapitsky, Y., Determining the colloidal behavior of ionically crosslinked polyelectrolytes with isothermal titration calorimetry. J. Phys. Chem. B 2013, 117, 9548-9557.
14. Huang, Y.; Lapitsky, Y., Salt-assisted mechanistic analysis of chitosan/ tripolyphosphate micro- and nanogel formation. Biomacromolecules 2012, 13, 3868-3876.
15. Huang, Y.; Lapitsky, Y., Monovalent salt enhances colloidal stability during the formation of chitosan/tripolyphosphate microgels. Langmuir 2011, 27, 10392-10399.
16. Richardson, K. E.; Xue, Z.; Huang, Y.; Seo, Y.; Lapitsky, Y., Physicochemical and antibacterial properties of surfactant mixtures with quaternized chitosan microgels. Carbohydr. Polym. 2013, 93, 709-717.

1.一种制备基于聚电解质的可溶性复合物的方法;ZL201911033161.X
2.一种梯度结构蛋白质水凝胶及其制备方法;ZL202010055510.4
3.Lapitsky, Y.; Huang, Y. Ionically Crosslinked Polyelectrolytes as Underwater Adhesives and Controlled Release Vehicles. US20160074516A1 (2016). (已产业化)

旗山学者启动基金：基于壳聚糖的离子交联微-纳米颗粒生成机理与性质研究。
国家自然科学基金青年基金：分子间作用对壳聚糖-反离子复合微纳米颗粒理化性质及递送效率的调控机制。
福建省自然科学基金面上基金：复合过程动力学对壳聚糖/反离子微-纳米颗粒性质的调控机理。
企业合作多项技术开发项目，部分项目已实现中试生产。

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