生物医药

1.以定制化细胞为主要模型，从细胞骨架、线粒体功能及细胞自噬等多种生物学功能入手，探索肿瘤发展机制。
2.利用分子生物学手段，开发多种用途的基因干预细胞模型。
3.高分辨成像的系统构建，以及基于显微技术的分析系统搭建。

1.Sijia Wang, Jing Ren, Jinghan Chi, Yifei Guan, Ran Zheng, Juan Wang, XinhuiLiu & Hua Huang (01 Apr 2025): RHOD mediates ATG9A trafficking to promote autophagosome formation during autophagy in cancer, Autophagy, DOI: 10.1080/15548627.2025.2484604
2.Hua Huang; Ruining Pan; Yue Zhao; Huan Li; Huiyu Zhu; Sijia Wang; Aamir Ali Khan; Juan Wang; Xinhui Liu; L3MBTL2-mediated CGA transcriptional suppression promotes pancreatic cancer progression through modulating autophagy, iScience, 2022, 25(5): 104249
3.Guan Y, Liu L, Wang W, Zheng R, Lin P, Liu Y, Chen S, Zhu H, Liu X, Huang H. Reniformin A Suppresses Triple-Negative Breast Cancer Progression by Inducing DRP1-Mediated Mitochondrial Dysfunction and Apoptosis. Phytother Res. 2025 Sep;39(9):4011-4027. doi: 10.1002/ptr.70034. Epub 2025 Jul 27. PMID: 40717184.
4.Hua Huang; Huan Li; Ruining Pan; Sijia Wang; Aamir Ali Khan; Yue Zhao; Huiyu Zhu; Xinhui Liu ; Ribosome 18S m 6 A methyltransferase METTL5 promotes pancreatic cancer progression by modulating c-Myc translation, International Journal of Oncology, 2022, 60(1)
5.Aamir Ali Khan; Hua Huang; Yue Zhao; Huan Li; Ruining Pan; Sijia Wang; Xinhui Liu ;WBSCR22 and TRMT112 synergistically suppress cell proliferation, invasion and tumorigenesis in pancreatic cancer via transcriptional regulation of ISG15, International Journal of Oncology,2022, 60(3): 24

1.用于药物筛选的钙离子通道工程细胞株构建，40万，在研
2.基于启动子融合的肿瘤精准基因治疗新方法研发，15万，结题
3.基于倒置荧光显微镜-毛细管电泳搭建单细胞蛋白互作检测体系，40万，在研