生物医药

有机电化学、药物合成

1. Zhoumei Tan, Yangye Jiang, Kun Xu, Chengchu Zeng, Electrophotoredox/cerium-catalyzed unactivated alkanes activation for the sustainable synthesis of alkylated benzimidazo-fused isoquinolinones, Journal of Catalysis,2023, 417, 473–480.
2. Fei Lian, Kun Xu & Chengchu Zeng, The synergism of sequential paired electrosynthesis with halogen bonding activation for the cyclization of organochlorides with olefins, Sci. China. Chem., 2023, 66(2), 540-547
3. Fei Lian, Feixian Luo, Meng Wang, Kun Xu,* and Chengchu Zeng，Electrochemical Atom Transfer Radical Addition of Polychloroalkanes to Olefins Promoted by 4,4-Di-tert-butyl Bipyridine, Chin. J. Chem. 2023, 41, 1583—1588.
4. Fei Lian, Kun Xu and Chengchu Zeng，Electrochemical umpolung enabled radical-radical cross-coupling between electron-deficient methylarenes and aldehydes, CCS Chem. 2023 DOI: 10.31635/ccschem.023.202302925
5. Zhoumei Tan, Xinrui He, Kun Xu Chengchu Zeng，Electrophotocatalytic C-H Functionalization of Heteroarenes with Unactivated Alkanes under external oxidant-free conditions, ChemSusChem 2022, 15, e202102360
6. Zhoumei Tan, Fang Xiang, Kun Xu, and Chengchu Zeng, Electrochemical Organoselenium-Catalyzed Intermolecular Hydroazolylation of Alkenes with Low Catalyst Loadings，Org. lett., 2022, 24, 5345−5350.
7. Haonan Zhang, Sen Liang, Dengchao Wei, Kun Xu, and Chengchu Zeng, Electrocatalytic Generation of Acyl Radicals and Their Applications, Eur. J. Org. Chem. 2022, e202200794
8. Xu Cheng, Aiwen Lei, Tian-Sheng Mei, Hai-Chao Xu, Kun Xu & Chengchu Zeng, Recent Applications of Homogeneous Catalysis in Electrochemical Organic Synthesis, CCS Chem. 2022, 4, 1120–1152.
9. Yangye Jiang, Kun Xu & Chengchu Zeng Electrophotocatalytic Si–H Activation Governed by Polarity-Matching Effects, CCS Chem. 2021, 3, 1911–1920
10. Fei Lian, Kun Xu, and Chengchu Zeng, Indirect Electrosynthesis with Halogen Ions as Mediators, Chem. Rec. 2021, 21, 2290– 2305
11. Cong Ma, Ping Fang, Zhao-Ran Liu, Shi-Shuo Xu, Kun Xu, Xu Cheng, Aiwen Lei, Hai-Chao Xu, Chengchu Zeng, Tian-Sheng Mei, Recent advances in organic electrosynthesis employing transition metal complexes as electrocatalysts, Science Bulletin, 2021, 66, 2412–2429.
12. Haonan Zhang, Ting Wang, Kun Xu, and Chengchu Zeng, N‑Hydroxyphthalimide-Mediated Electrochemical Denitrogenation of Aroylhydrazides to Generate Acyl Radicals and Their Applications in the Syntheses of Fluorenones, J. Org. Chem. 2021, 86, 16171−16176.

1. 国家自然科学基金（22271009）：电催化与成对电合成耦合的氧化还原中性自由基交叉偶联反应研究 （2023/01-2026/12）
2. 北京市教委科技计划重点项目（KZ202110005003）：基于电催化的成对电合成在净中性自由基极性交叉反应中的应用研究 （2021/01-2023/12）
3. 国家自然科学基金（21871019）：碳自由基的电化学可控形成及其在Minisci 反应中的应用（2018/01-2022/12）
4. 国家重点研发计划课题：基于卤素离子的间接电催化氧化合成关键技术及其示范（2017/07-2020/12）
5. 国家重点研发计划子课题：食用香料香精和配料绿色制造关键技术研究（2016/7-2020/12）
6. 企业委托项目：香料的电化学合成研究（2015/01-2019/12）
7. 国家自然科学基金（21472011）：卤素离子为媒介的电化学氧化偶联形成新的C-C键或C-N键的研究（2015/01-2018/12）
8. 国家自然科学基金（21272021）：新型三芳基咪唑类有机电催化剂的创制及其电氧化活化C-H键和C-C键研究（2013/01-2016/12）
9. 国家自然科学基金（20772010）水相中邻苯醌衍生物的电化学合成与原位转化（2008/01-2010/12）
10. 国家自然科学基金（20402001）磺酰胺苯乙烯基喹啉: 新型HIV整合酶抑制剂的设计、合成及其构效关系研究（ 2005/01-2007/12）