专家介绍:
主要从事细胞力学响应与界面生物材料相关研究工作,具备材料学、化学、生物学复合背景,在细胞粘附与力学信号转导,以及高分子化学与材料表面改性等领域均有充分的研究经历。在Advanced Materials、Nano Letters、ACS Nano、Advanced Science、Angewandte Chemie International Edition等主流杂志上发表论文50余篇,论文引总数超过4000次,H-index为32。其中通讯作者与一作者论文30余篇,平均影响因子>10,多篇进入ESI高被引论文,单篇最高引用>600。另授权专利多项。担任国际期刊Smart Materials in Medicine、Materials Research Express、Biosensors与Frontiers in Bioengineering and Biotechnology编委,担任Polymers等期刊的客座编辑,并为ACS、RSC、Wiley、Elsevier等多个主流数据库的众多SCI杂志审稿人,多次受邀为仲裁审稿人。课题组依托于四川大学高分子科学与工程学院以及高分子材料与工程国家重点实验室,与华西医院、国家生物医学材料工程保持紧密合作,并与来自香港、德国、加拿大、荷兰、英国、以色列等众多世界知名大学和研究机构的课题组展开合作与学术交流。代表论文:1、BMP-2 Signaling and Mechanotransduction Synergize to Drive Osteogenic Differentiation via YAP/TAZ.Adv. Sci.DOI: 10.1002/advs.201902931.2、Surface Roughness and Substrate Stiffness Synergize to Drive Cellular Mechanoresponse.Nano Lett.2020, 1, 748-757.3、Surface roughness gradients reveal topography-specific mechanosensitive responses in human mesenchymal stem cells.Small2020, 16, 1905422.4、Nanopatterned Adhesive, Stretchable Hydrogel to Control Ligand Spacing and Regulate Cell Spreading and Migration.ACS Nano2017, 11, 8282-8291.5、Universal Polymer Coatings and Their Representative Biomedical Applications.Mater. Horiz.2015, 2, 567-577.6、Mussel-Inspired Dendritic Polymers as Universal Multifunctional Coatings.Angew. Chem. Int. Ed.2014, 53, 11650-11655.7、Protein Interactions with Polymer Coatings and Biomaterials.Angew. Chem. Int. Ed.2014, 53, 8004-8031.8、Supramolecular Polymers as Surface Coatings: Rapid Fabrication of Healable Superhydrophobic and Slippery Surfaces.Adv. Mater.2014, 26, 7358–7364.9、A Universal Approach to Crosslinked Hierarchical Polymer Multilayers as Stable and Highly Effective Antifouling Coatings.Adv. Mater.2014, 26, 2688-2693.