精细化工

[1] 仿生不对称催化
[2] 仿生全合成
[3] 新反应发展

[1]Jianfeng Chen,1,2‡ Xing Gong,1‡ Jianyu Li,1 Yingkun Li,1 Jiguo Ma,1 Chengkang Hou,1 Guoqing Zhao,1 Weicheng Yuan,2*Baoguo Zhao1* “Carbonyl Catalysis Enables a Biomimetic Asymmetric Mannich Reaction” Science2018, 360, 1438. (‡equally contributed).
[2]Jiguo Ma,‡ Bin Gao,‡ Guanshui Song, Ruixin Zhang, Qingfang Wang, Zi Ye, Wen-Wen Chen,* Baoguo Zhao* Asymmetric-Allylation of Glycinate with Switched Chemoselectivity Enabled by Customized Bifunctional Pyridoxal Catalysts. Angew. Chem., Int. Ed.2022, 10.1002/anie.202200850. (‡equally contributed).
[3]Bingfei Peng,‡ Jiguo Ma,‡ Jianhua Guo,‡ Yating Gong, Ronghao Wang, Yi Zhang, Jinlong Zeng, Wen-Wen Chen,* Kuiling Ding,* Baoguo Zhao* A Powerful Chiral Super Brønsted C–H Acid for Asymmetric Catalysis. J. Am. Chem. Soc.2022, 144, 2853. (‡equally contributed).
[4]Aolin Cheng, Liangliang Zhang, Qinghai Zhou, Tao Liu, Jing Cao, Guoqing Zhao,* Kun Zhang, Guanshui Song, Baoguo Zhao* Efficient Asymmetric Biomimetic Aldol Reaction of Glycinates and Trifluoromethyl Ketones by Carbonyl Catalysis. Angew. Chem., Int. Ed.2021, 60, 20166.
[5]Jiguo Ma, Qinghai Zhou, Guanshui Song,Y ongchang Song, Guoqing Zhao, Kuiling Ding, Baoguo Zhao* Enantioselective Synthesis of Pyroglutamic Acid Esters from Glycinate via Carbonyl Catalysis. Angew. Chem., Int. Ed. 2021, 60, 10588.
[6]Weiqi Cai, Xuelong Qiao, Hao Zhang, Bo Li, Jianhua Guo, Liangliang Zhang, Wen-Wen Chen, Baoguo Zhao* Asymmetric biomimetic transamination of α-keto amides to peptides. Nat. Commun.2021, 12, 5174.
[7]Yong Ethan Liu, Zhaole Lu, Bo Li, Jiaxin Tian, Feng Liu, Junyu Zhao, Chengkang Hou, Yingkun Li, Lili Niu, Baoguo Zhao* “Enzyme-Inspired Axially Chiral Pyridoxamines Armed with a Cooperative Lateral Amine Chain for Enantioselective Biomimetic Transamination”J. Am. Chem. Soc. 2016, 138, 10730.
[8] Limin Shi, Chuangan Tao, Qin Yang, Yong Ethan Liu, Jing Chen, Jianfeng Chen, Jiaxin Tian, Feng Liu, Bo Li, Yongling Du, Baoguo Zhao* “Chiral Pyridoxal-Catalyzed Asymmetric Biomimetic Transamination of α-Keto Acids” Org. Lett.2015, 17, 5784.
[9]Lei Ding, Jing Chen, Yifan Hu, Juan Xu, Xing Gong, Dongfang Xu, Baoguo Zhao*, Hexing Li “Aminative Umpolung of Aldehydes to α-Amimo Anion Equivalents for Pd-catalyzed Allyation: An Efficient Synthesis of Homoallylic Amines” Org. Lett.2014, 16, 720.
[10]Baoguo Zhao, Zhaobin Han, Kuiling Ding* “N-H Functions in Organometallic Catalysis” Angew. Chem. Int. Ed.2013, 52, 4744.

[1] 赵宝国，刘勇，卢兆乐，李波，“一种手性联芳骨架吡哆胺类催化剂及其合成方法与应用”，申请号：201610444057.X。
[2] 赵宝国，陈剑锋，赵濬宇，龚幸，“一种新型手性开链吡哆胺催化剂及其合成方法与应用”，专利号：201610444112.5。
[3] 赵宝国，兰晓宇，陶创安，刘旭亮，“一种手性吡哆胺催化剂及其合成方法和应用”，专利号：201610443128.4。
[4] 赵宝国，陈静，石力敏，刘勇，杨琴，陈剑锋，田家昕，陶创安，李波，许东芳“一种新型吡哆素衍生物及其制备方法”，专利号：201510413900.3。
[5] 赵宝国，陈静，杨琴，陈剑锋，石力敏，刘勇（Yong Ethan Liu），龚幸，兰晓宇，卢兆乐，刘勇 (Yong Liu)，陶创安，田家昕，许东芳，“一种吡哆醛催化剂及其合成方法与应用”，专利号：201510415046.4。
[6] 赵宝国，陶创安，石力敏，刘勇，陈静，“一种手性吡哆醛催化剂及其合成方法与应用”，专利号：201510427177.4。

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