精细化工

I、有机反应机理研究（理论计算）环境污染物降解机制、催化反应机理、选择性控制等；
II、功能分子的设计、合成及性能新型抗氧化剂、功能药物载体、医药中间体等；
III、顺磁共振在化学、生物学研究中的应用生物分子间相互作用、反应中间体检测等。

主持国家自然科学基金两项、天津市应用基础与前沿技术研究计划（重点项目）一项及中科院环境化学与生态毒理学国家重点实验室基金一项。 参与国家自然科学基金项目及天津市应用基础研究基金项目多项。目前为止，以第一作者或通讯作者在J.Am.Chem.Soc.、Angew.Chem.Int.Ed.、Macromolecules、 J.Org.Chem.、 Chem.Comm.、 Org.Lett.、 J.Mater.Chem.B、Sci. Chi-Chem等学术期刊发表论文60余篇，申请专利两项。

(1) Nano CaCO3 'Lysosomal Bombs' Enhance Chemotherapy Drug Efficacy via Rebalancing Tumor Intracellular pH, ACS Biomaterials Science & Engineering, 2019, 5, 3398-3408;
(2) Double Dehydrogenation of Carbocyclic-dicarbonyl Compounds: Koser's Reagent Can Do What Iodine(V) Reagents Can?, Sci. Chi.-Chem., 2019, 62, 597-601;
(3) An ROS-responsive and Self-accelerating Drug Release Nanoplatform for Overcoming Multidrug Resistance, Chem. Comm., 2019, 55, 3383-3386;
(4) Waste Recycling: Ionic Liquid-Catalyzed 4-Electron Reduction of CO2 with Amines and Polymethylhydrosiloxane Combining Experimental and Theoretical Study, ACS Sustainable Chemistry & Engineering, 2018, 6, 8130-8135;
(5) Mechanisms of Metal-Free Aerobic Oxidation To Prepare Benzoxazole Catalyzed by Cyanide: A Direct Cyclization or Stepwise Oxidative Dehydrogenation and Cyclization?, J. Org. Chem., 2016, 81, 10857-10862;
(6) Modulating the Cellular Microenvironment with Disulfide-containing Nanoparticles as an Auxiliary Cancer Treatment Strategy, J. Mater. Chem. B, 2016, 4, 3868-3873;
(7) Palladium-Catalyzed Carboxylation of Benzyl Chlorides with Atmospheric Carbon Dioxide in Combination with Manganese/Magnesium Chloride, CHEMCATCHEM, 2015, 7, 3972-3977;
(8) A Combined Experimental and Computational Investigation on the Unusual Molecular Mechanism of the Lossen Rearrangement Reaction Activated by Carcinogenic Halogenated Quinones, J. Org. Chem., 2015, 80, 180-189;
(9) Quantum dot self-decorated TiO2 nanosheets, Chem. Comm., 2013, 49 6593-6595;
(10) Mechanism and Selectivity of Bioinspired Cinchona Alkaloid Derivatives Catalyzed Asymmetric Olefin Isomerization: a Computational Study, J. Am. Chem. Soc., 2013, 135, 7462-7473;