天然气化工,新材料,石油炼制,石油化工,精细化工,生物医药

复杂天然产物的全合成、有机合成方法学、药物化学

Total Synthesis;Natural Products;Antibiotics;Metathesis;Cyclization;Alkaloids;Asymmetric Synthesis;Palladium;Macrocycles;Structure-activity Relationships

1. Silver-catalyzed C2-selective direct alkylation of heteroarenes with tertiary cycloalkanols
Shi-Chao Lu; Hong-Shuang Li; Shu Xu; Gui-Yun Duan
Organic & Biomolecular Chemistry, 2017

2. Discovery of a Novel Series of Semisynthetic Vancomycin Derivatives Effective Against Vancomycin-Resistant Bacteria.
Yuki Nakama; Osamu Yoshida; Masanori Yoda; Keisuke Araki; Yuri Sawada; Jun Nakamura; Shu Xu; Kenji Miura; Hideki Maki; Hirokazu Arimoto
Journal of Medicinal Chemistry, 2010

3. Asymmetric Total Synthesis of Pinnaic Acid
Shu Xu; Hirokazu Arimoto; Daisuke Uemura
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007

4. Enantioselective Total Synthesis of Pinnaic Acid and Halichlorine
Shu Xu; Daisuke Unabara; Daisuke Uemura; Hirokazu Arimoto
CHEMISTRY-AN ASIAN JOURNAL, 2014

5. Combination of PhI(OAc)(2) and 2-Nitropropane As the Source of Methyl Radical in Room-Temperature Metal-Free Oxidative Decarboxylation/Cyclization: Construction of 6-Methyl Phenanthridines and 1-Methyl Isoquinolines
Shi-Chao Lu; Hong-Shuang Li; Ya-Ling Gong; Shi-Peng Zhang; Ji-Guo Zhang; Shu Xu
JOURNAL OF ORGANIC CHEMISTRY, 2018

6. One-Pot Reductive Cleavage of Exo-Olefin to Methylene with A Mild Ozonolysis-Clemmensen Reduction Sequence
Shu Xu; Takayuki Toyama; Jun Nakamura; Hirokazu Arimoto
TETRAHEDRON LETTERS, 2010

7. Unexpected Dehomologation of Primary Alcohols to One-Carbon Shorter Carboxylic Acids Using O-Iodoxybenzoic Acid (IBX).
Shu Xu; Kaori Itto; Masahide Satoh; Hirokazu Arimoto
Chemical Communications, 2014

8. Total Synthesis of the Antibiotic Kendomycin: A Macrocyclization Using the Tsuji-Trost Etherification
Tetsuya Sengoku; Shu Xu; Kenji Ogura; Yoshinori Emori; Kenji Kitada; Daisuke Uemura; Hirokazu Arimoto
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014

9. New Insight into the Mode of Action of Vancomycin Dimers in Bacterial Cell Wall Synthesis
Osamu Yoshida; Jun Nakamura; Hidenori Yamashiro; Kenji Miura; Sayaka Hayashi; Kosei Umetsu; Shu Xu; Hideki Maki; Hirokazu Arimoto
MEDCHEMCOMM, 2011

10. Novel Blood-Brain Barrier-Permeable Spin Probe for in Vivo Electron Paramagnetic Resonance Imaging.
Xiaolei Wang; Miho Emoto; Yusuke Miyake; Kaori Itto; Shu Xu; Hirotada Fujii; Hiroshi Hirata; Hirokazu Arimoto
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016

1. 一种派恩加滨的制备方法
中国医学科学院药物研究所
许述; 孙艺菁; 张世鹏; 弓亚玲; 卢诗超
公开日期: 2024-08-23 申请日期: 2023-02-21 公开号: CN118530144A

2. 一种盐酸普拉克索有关物质的制备方法
中国医学科学院药物研究所
许述; 弓亚玲; 纪春阳; 卢诗超; 张世鹏
公开日期: 2023-11-14 申请日期: 2022-05-07 公开号: CN117050033A

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